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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRHBP All Species: 14.85
Human Site: S234 Identified Species: 29.7
UniProt: P24387 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24387 NP_001873.2 322 36144 S234 G L Q L K K S S A G C E G I G
Chimpanzee Pan troglodytes XP_517697 260 28822 G174 Q L K K S S A G C E G I G D F
Rhesus Macaque Macaca mulatta XP_001106453 322 36227 S234 G L Q L K K S S A G C E G I G
Dog Lupus familis XP_853211 590 64286 S502 G L Q L K N P S A G C G G I G
Cat Felis silvestris
Mouse Mus musculus Q60571 322 36029 A234 G L Q L K K P A A G C G G T G
Rat Rattus norvegicus P24388 322 36102 A234 G L Q L K K P A A G C G G T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513926 335 37640 S227 D L Q Q K S P S E G C G R A G
Chicken Gallus gallus XP_424801 355 39361 S267 G L F L K N P S V G C A G V G
Frog Xenopus laevis Q91653 321 36276 P233 E L Q L K K P P P K G C G D A
Zebra Danio Brachydanio rerio NP_001003459 321 35983 I234 H N D L K R S I L G C A G S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097981 353 38133 S263 S L R I G G K S V R A Q P K V
Honey Bee Apis mellifera NP_001012633 332 37518 A246 F L S S T R T A E T G T I R K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.7 97.8 46.2 N.A. 87.2 84.4 N.A. 37.9 67.6 68.3 62.7 N.A. 26 26.2 N.A. N.A.
Protein Similarity: 100 80.7 98.7 50.6 N.A. 93.1 90.6 N.A. 52.5 78.8 78.2 78.8 N.A. 41.9 46.3 N.A. N.A.
P-Site Identity: 100 13.3 100 80 N.A. 73.3 73.3 N.A. 46.6 60 40 46.6 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 26.6 100 80 N.A. 80 80 N.A. 46.6 66.6 40 53.3 N.A. 33.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 25 42 0 9 17 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 67 9 0 0 0 % C
% Asp: 9 0 9 0 0 0 0 0 0 0 0 0 0 17 0 % D
% Glu: 9 0 0 0 0 0 0 0 17 9 0 17 0 0 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 50 0 0 0 9 9 0 9 0 67 25 34 75 0 67 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 9 0 0 0 9 9 25 0 % I
% Lys: 0 0 9 9 75 42 9 0 0 9 0 0 0 9 9 % K
% Leu: 0 92 0 67 0 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 17 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 50 9 9 0 0 0 9 0 0 % P
% Gln: 9 0 59 9 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 0 0 9 0 0 17 0 0 0 9 0 0 9 9 0 % R
% Ser: 9 0 9 9 9 17 25 50 0 0 0 0 0 9 0 % S
% Thr: 0 0 0 0 9 0 9 0 0 9 0 9 0 17 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _