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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL4R
All Species:
7.88
Human Site:
T757
Identified Species:
28.89
UniProt:
P24394
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24394
NP_000409.1
825
89658
T757
D
R
S
S
P
P
T
T
P
L
R
A
P
D
P
Chimpanzee
Pan troglodytes
XP_001136123
825
89649
T757
D
R
S
S
P
P
T
T
P
L
R
A
P
D
P
Rhesus Macaque
Macaca mulatta
XP_001093763
731
80174
P664
R
S
S
P
P
T
T
P
L
R
A
P
D
P
S
Dog
Lupus familis
XP_547077
890
94637
S822
D
R
S
S
L
L
L
S
P
L
R
A
P
N
V
Cat
Felis silvestris
Mouse
Mus musculus
P16382
810
87609
C742
V
A
S
P
G
C
G
C
C
Y
D
D
R
S
P
Rat
Rattus norvegicus
Q63257
801
86700
C733
V
A
S
P
G
C
G
C
C
Y
D
E
K
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414885
996
110745
L924
L
K
T
A
E
E
P
L
E
L
L
V
S
D
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
80.3
60
N.A.
52.3
51.6
N.A.
N.A.
22.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
83.1
68.4
N.A.
63.8
64.4
N.A.
N.A.
37.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
60
N.A.
13.3
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
73.3
N.A.
13.3
13.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
0
15
0
0
0
0
0
0
15
43
0
0
0
% A
% Cys:
0
0
0
0
0
29
0
29
29
0
0
0
0
0
0
% C
% Asp:
43
0
0
0
0
0
0
0
0
0
29
15
15
43
0
% D
% Glu:
0
0
0
0
15
15
0
0
15
0
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
29
0
29
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
0
0
0
0
0
0
0
0
0
0
15
0
15
% K
% Leu:
15
0
0
0
15
15
15
15
15
58
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% N
% Pro:
0
0
0
43
43
29
15
15
43
0
0
15
43
15
58
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
43
0
0
0
0
0
0
0
15
43
0
15
0
0
% R
% Ser:
0
15
86
43
0
0
0
15
0
0
0
0
15
29
15
% S
% Thr:
0
0
15
0
0
15
43
29
0
0
0
0
0
0
0
% T
% Val:
29
0
0
0
0
0
0
0
0
0
0
15
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _