KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GADD45A
All Species:
18.18
Human Site:
S133
Identified Species:
44.44
UniProt:
P24522
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24522
NP_001915.1
165
18336
S133
L
V
T
N
P
H
S
S
Q
W
K
D
P
A
L
Chimpanzee
Pan troglodytes
XP_001164496
131
14604
A105
S
S
Q
W
K
D
P
A
L
S
Q
L
I
C
F
Rhesus Macaque
Macaca mulatta
XP_001095413
165
18331
S133
L
V
T
N
P
H
S
S
Q
W
K
D
P
A
L
Dog
Lupus familis
XP_542187
160
17756
D128
L
V
T
N
P
H
T
D
A
W
K
S
H
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P48316
165
18320
S133
L
V
T
N
P
H
S
S
Q
W
K
D
P
A
L
Rat
Rattus norvegicus
P48317
165
18461
S133
L
V
T
N
P
H
S
S
Q
W
K
D
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512623
321
33644
S289
L
V
T
N
P
H
S
S
Q
W
K
D
P
A
L
Chicken
Gallus gallus
P84175
132
14526
C106
K
P
R
K
V
V
G
C
S
C
V
V
V
K
D
Frog
Xenopus laevis
P47840
132
14482
C106
K
P
R
K
V
V
G
C
S
C
V
V
V
K
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P80455
139
15150
C113
K
P
R
K
V
C
G
C
S
V
V
V
I
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
99.3
55.1
N.A.
94.5
92.1
N.A.
47.6
25.4
26.6
N.A.
N.A.
23.6
N.A.
N.A.
N.A.
Protein Similarity:
100
79.3
100
72.7
N.A.
95.1
92.7
N.A.
48.9
43
43
N.A.
N.A.
42.4
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
60
N.A.
100
100
N.A.
100
0
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
66.6
N.A.
100
100
N.A.
100
0
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
10
0
30
0
20
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
50
0
0
30
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
30
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
60
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
30
0
0
30
10
0
0
0
0
0
60
0
0
30
0
% K
% Leu:
60
0
0
0
0
0
0
0
10
0
0
10
0
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
30
0
0
60
0
10
0
0
0
0
0
50
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
50
0
10
0
0
0
0
% Q
% Arg:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
50
50
30
10
0
10
0
0
0
% S
% Thr:
0
0
60
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
60
0
0
30
20
0
0
0
10
30
30
20
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
60
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _