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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GADD45A
All Species:
22.12
Human Site:
Y41
Identified Species:
54.07
UniProt:
P24522
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24522
NP_001915.1
165
18336
Y41
R
T
I
T
V
G
V
Y
E
A
A
K
L
L
N
Chimpanzee
Pan troglodytes
XP_001164496
131
14604
V35
D
E
D
D
D
R
D
V
A
L
Q
I
H
F
T
Rhesus Macaque
Macaca mulatta
XP_001095413
165
18331
Y41
R
T
I
T
V
G
V
Y
E
A
A
K
L
L
N
Dog
Lupus familis
XP_542187
160
17756
Y41
D
R
L
T
V
G
V
Y
E
S
A
K
L
M
N
Cat
Felis silvestris
Mouse
Mus musculus
P48316
165
18320
Y41
R
T
I
T
V
G
V
Y
E
A
A
K
L
L
N
Rat
Rattus norvegicus
P48317
165
18461
Y41
R
T
I
T
V
G
V
Y
E
A
A
K
L
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512623
321
33644
Y201
R
T
I
T
V
G
V
Y
E
A
A
K
L
L
N
Chicken
Gallus gallus
P84175
132
14526
R36
D
G
L
A
R
G
I
R
E
A
A
K
A
L
D
Frog
Xenopus laevis
P47840
132
14482
R36
D
G
L
A
R
G
I
R
E
A
A
K
A
L
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P80455
139
15150
H43
D
G
L
V
H
G
I
H
Q
A
C
K
A
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
99.3
55.1
N.A.
94.5
92.1
N.A.
47.6
25.4
26.6
N.A.
N.A.
23.6
N.A.
N.A.
N.A.
Protein Similarity:
100
79.3
100
72.7
N.A.
95.1
92.7
N.A.
48.9
43
43
N.A.
N.A.
42.4
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
66.6
N.A.
100
100
N.A.
100
40
40
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
86.6
N.A.
100
100
N.A.
100
60
60
N.A.
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
10
80
80
0
30
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
50
0
10
10
10
0
10
0
0
0
0
0
0
0
30
% D
% Glu:
0
10
0
0
0
0
0
0
80
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
30
0
0
0
90
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% H
% Ile:
0
0
50
0
0
0
30
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% K
% Leu:
0
0
40
0
0
0
0
0
0
10
0
0
60
80
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
50
10
0
0
20
10
0
20
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% S
% Thr:
0
50
0
60
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
10
60
0
60
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _