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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDNRB
All Species:
8.79
Human Site:
Y251
Identified Species:
17.58
UniProt:
P24530
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24530
NP_000106.1
442
49644
Y251
T
M
D
Y
K
G
S
Y
L
R
I
C
L
L
H
Chimpanzee
Pan troglodytes
XP_509693
532
59607
Y341
T
M
D
Y
K
G
S
Y
L
R
I
C
L
L
H
Rhesus Macaque
Macaca mulatta
Q6H2Y3
398
44247
I215
S
K
K
L
L
Q
E
I
H
S
L
L
C
F
L
Dog
Lupus familis
XP_853465
426
48505
M239
G
E
Q
H
K
T
C
M
L
N
A
T
S
K
F
Cat
Felis silvestris
Mouse
Mus musculus
P48302
442
49542
P251
T
S
D
Y
K
G
K
P
L
R
V
C
M
L
N
Rat
Rattus norvegicus
P21451
442
49436
P251
T
S
D
Y
K
G
K
P
L
R
V
C
M
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508459
342
39596
P159
L
R
I
C
F
L
H
P
T
Q
K
T
P
F
M
Chicken
Gallus gallus
NP_001001127
439
49051
D249
T
M
E
Y
R
G
K
D
L
R
I
C
L
L
H
Frog
Xenopus laevis
P32940
444
50154
F248
P
M
E
Q
T
S
D
F
M
R
F
Y
Q
E
V
Zebra Danio
Brachydanio rerio
Q7SZP9
362
40631
S179
T
T
V
D
D
T
G
S
N
R
T
T
C
A
M
Tiger Blowfish
Takifugu rubipres
NP_001092135
468
52079
T257
T
F
H
Y
N
N
Q
T
M
R
T
C
M
L
N
Fruit Fly
Dros. melanogaster
P30974
504
58001
S297
N
T
D
R
Q
M
E
S
M
K
S
K
R
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
28
55.2
N.A.
88.9
88.9
N.A.
65.6
79.1
50
24.2
48.5
22.8
N.A.
N.A.
N.A.
Protein Similarity:
100
83
46.8
71.9
N.A.
93.4
93.2
N.A.
71.4
84.3
67.3
38.2
61.5
39
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
60
60
N.A.
0
73.3
13.3
13.3
33.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
80
80
N.A.
6.6
86.6
33.3
13.3
53.3
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
9
0
0
9
0
0
0
0
50
17
0
0
% C
% Asp:
0
0
42
9
9
0
9
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
17
0
0
0
17
0
0
0
0
0
0
9
0
% E
% Phe:
0
9
0
0
9
0
0
9
0
0
9
0
0
17
9
% F
% Gly:
9
0
0
0
0
42
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
9
0
0
9
0
9
0
0
0
0
0
25
% H
% Ile:
0
0
9
0
0
0
0
9
0
0
25
0
0
0
0
% I
% Lys:
0
9
9
0
42
0
25
0
0
9
9
9
0
17
0
% K
% Leu:
9
0
0
9
9
9
0
0
50
0
9
9
25
50
9
% L
% Met:
0
34
0
0
0
9
0
9
25
0
0
0
25
0
17
% M
% Asn:
9
0
0
0
9
9
0
0
9
9
0
0
0
0
25
% N
% Pro:
9
0
0
0
0
0
0
25
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
9
9
9
9
0
0
9
0
0
9
0
0
% Q
% Arg:
0
9
0
9
9
0
0
0
0
67
0
0
9
0
0
% R
% Ser:
9
17
0
0
0
9
17
17
0
9
9
0
9
0
0
% S
% Thr:
59
17
0
0
9
17
0
9
9
0
17
25
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
17
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
17
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _