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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEF1B2
All Species:
26.97
Human Site:
S106
Identified Species:
39.56
UniProt:
P24534
Number Species:
15
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24534
NP_001032752.1
225
24764
S106
D
D
I
D
L
F
G
S
D
D
E
E
E
S
E
Chimpanzee
Pan troglodytes
XP_001135927
356
39044
S237
D
D
I
D
L
F
G
S
D
D
E
E
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001106040
225
24715
S106
D
D
I
D
L
F
G
S
D
D
E
E
E
S
E
Dog
Lupus familis
XP_536040
225
24802
S106
D
D
I
D
L
F
G
S
D
D
E
E
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
O70251
225
24675
S106
D
D
I
D
L
F
G
S
D
D
E
E
E
S
E
Rat
Rattus norvegicus
Q68FR9
281
31312
S162
N
D
I
D
L
F
G
S
D
E
E
E
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507454
203
22437
E88
L
F
G
S
D
D
E
E
E
S
E
E
A
K
R
Chicken
Gallus gallus
Q9YGQ1
225
24743
S106
D
D
I
D
L
F
G
S
D
D
E
E
E
S
E
Frog
Xenopus laevis
P30151
227
25157
F106
D
D
D
D
I
D
L
F
G
S
D
D
E
E
E
Zebra Danio
Brachydanio rerio
NP_956243
225
24467
G106
D
D
D
I
D
L
F
G
S
D
E
E
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O96827
222
24229
D106
V
D
L
F
G
S
D
D
E
E
D
E
E
A
E
Honey Bee
Apis mellifera
XP_625027
217
24596
E103
L
F
E
S
D
E
E
E
D
P
E
A
V
R
L
Nematode Worm
Caenorhab. elegans
P34460
213
22686
D99
G
S
D
D
E
E
E
D
A
E
K
A
K
I
V
Sea Urchin
Strong. purpuratus
NP_001118232
218
23536
C104
D
D
D
D
D
F
D
C
F
G
S
D
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SI20
231
25248
D109
A
E
E
E
D
D
D
D
V
D
L
F
G
E
E
Baker's Yeast
Sacchar. cerevisiae
P32471
206
22609
D92
G
S
D
D
E
E
A
D
A
E
A
E
K
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.2
99.5
98.2
N.A.
95.5
46.9
N.A.
84.8
96.8
84.5
82.2
N.A.
57.7
57.3
50.6
54.6
Protein Similarity:
100
63.2
99.5
99.1
N.A.
98.2
59
N.A.
88.8
98.6
94.7
91.1
N.A.
75.5
72.4
65.7
68
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
13.3
100
33.3
46.6
N.A.
26.6
13.3
6.6
40
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
20
100
53.3
46.6
N.A.
60
13.3
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.1
47.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
0
13
0
7
13
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
57
69
32
69
32
19
19
25
50
50
13
13
0
13
0
% D
% Glu:
0
7
13
7
13
19
19
13
13
25
63
69
69
19
69
% E
% Phe:
0
13
0
7
0
50
7
7
7
0
0
7
0
0
0
% F
% Gly:
13
0
7
0
7
0
44
7
7
7
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
44
7
7
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
7
0
13
7
13
% K
% Leu:
13
0
7
0
44
7
7
0
0
0
7
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% R
% Ser:
0
13
0
13
0
7
0
44
7
13
7
0
0
38
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
7
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _