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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EEF1B2 All Species: 34.55
Human Site: S141 Identified Species: 50.67
UniProt: P24534 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24534 NP_001032752.1 225 24764 S141 P A L V A K S S I L L D V K P
Chimpanzee Pan troglodytes XP_001135927 356 39044 S272 P A L V A K S S I L L D V K P
Rhesus Macaque Macaca mulatta XP_001106040 225 24715 S141 P A L V A K S S I L L D V K P
Dog Lupus familis XP_536040 225 24802 S141 P A L V A K S S I L L D V K P
Cat Felis silvestris
Mouse Mus musculus O70251 225 24675 S141 P A V V A K S S I L L D V K P
Rat Rattus norvegicus Q68FR9 281 31312 S197 P T L V A K S S I L L D V K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507454 203 22437 D123 A K S S L L L D V K P W D D E
Chicken Gallus gallus Q9YGQ1 225 24743 S141 P A L V A K S S I L L D V K P
Frog Xenopus laevis P30151 227 25157 K141 K K P T L I A K S S I L L D V
Zebra Danio Brachydanio rerio NP_956243 225 24467 S141 P A L I A K S S I L L D V K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O96827 222 24229 L141 I A K S S V L L D V K P W D D
Honey Bee Apis mellifera XP_625027 217 24596 V138 K S S V V L D V K P W D D E T
Nematode Worm Caenorhab. elegans P34460 213 22686 K134 S S V I L D V K P W D D E T D
Sea Urchin Strong. purpuratus NP_001118232 218 23536 D139 A K S S V L F D V K P E D D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SI20 231 25248 S144 K K E S G K S S V L M D I K P
Baker's Yeast Sacchar. cerevisiae P32471 206 22609 V127 K S I V T L D V K P W D D E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.2 99.5 98.2 N.A. 95.5 46.9 N.A. 84.8 96.8 84.5 82.2 N.A. 57.7 57.3 50.6 54.6
Protein Similarity: 100 63.2 99.5 99.1 N.A. 98.2 59 N.A. 88.8 98.6 94.7 91.1 N.A. 75.5 72.4 65.7 68
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 100 0 93.3 N.A. 6.6 13.3 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 6.6 100 20 100 N.A. 20 26.6 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 47.1 47.5 N.A.
Protein Similarity: N.A. N.A. N.A. 61 63.5 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 50 0 0 50 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 13 13 7 0 7 75 25 25 13 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 0 7 7 13 13 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 7 13 0 7 0 0 50 0 7 0 7 0 0 % I
% Lys: 25 25 7 0 0 57 0 13 13 13 7 0 0 57 0 % K
% Leu: 0 0 44 0 19 25 13 7 0 57 50 7 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 0 7 0 0 0 0 0 7 13 13 7 0 0 57 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 19 19 25 7 0 57 57 7 7 0 0 0 0 0 % S
% Thr: 0 7 0 7 7 0 0 0 0 0 0 0 0 7 13 % T
% Val: 0 0 13 57 13 7 7 13 19 7 0 0 50 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 13 7 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _