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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEF1B2
All Species:
31.52
Human Site:
Y126
Identified Species:
46.22
UniProt:
P24534
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24534
NP_001032752.1
225
24764
Y126
R
E
E
R
L
A
Q
Y
E
S
K
K
A
K
K
Chimpanzee
Pan troglodytes
XP_001135927
356
39044
Y257
R
E
E
R
L
A
Q
Y
E
S
K
K
A
K
K
Rhesus Macaque
Macaca mulatta
XP_001106040
225
24715
Y126
R
E
E
R
L
A
Q
Y
E
S
K
K
A
K
K
Dog
Lupus familis
XP_536040
225
24802
Y126
R
E
E
R
L
A
Q
Y
E
S
K
K
A
K
K
Cat
Felis silvestris
Mouse
Mus musculus
O70251
225
24675
Y126
R
E
E
R
L
A
Q
Y
E
S
K
K
A
K
K
Rat
Rattus norvegicus
Q68FR9
281
31312
Y182
R
E
E
R
L
R
Q
Y
A
E
K
K
A
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507454
203
22437
K108
L
A
Q
Y
E
S
K
K
S
K
K
P
A
L
I
Chicken
Gallus gallus
Q9YGQ1
225
24743
Y126
R
E
E
R
L
A
Q
Y
E
S
K
K
A
K
K
Frog
Xenopus laevis
P30151
227
25157
A126
R
V
R
D
E
R
L
A
Q
Y
E
A
K
K
S
Zebra Danio
Brachydanio rerio
NP_956243
225
24467
Y126
K
E
E
R
L
A
A
Y
N
A
K
K
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O96827
222
24229
K126
R
V
A
A
Y
A
A
K
K
S
K
K
P
A
L
Honey Bee
Apis mellifera
XP_625027
217
24596
S123
K
E
Y
A
E
K
K
S
K
K
P
I
L
I
A
Nematode Worm
Caenorhab. elegans
P34460
213
22686
K119
A
Y
A
E
K
K
A
K
K
A
G
P
I
A
K
Sea Urchin
Strong. purpuratus
NP_001118232
218
23536
K124
P
K
T
K
I
E
V
K
K
P
K
K
V
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SI20
231
25248
A129
K
A
A
E
E
R
A
A
S
V
K
A
S
T
K
Baker's Yeast
Sacchar. cerevisiae
P32471
206
22609
A112
A
Y
N
A
K
K
A
A
K
P
A
K
P
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.2
99.5
98.2
N.A.
95.5
46.9
N.A.
84.8
96.8
84.5
82.2
N.A.
57.7
57.3
50.6
54.6
Protein Similarity:
100
63.2
99.5
99.1
N.A.
98.2
59
N.A.
88.8
98.6
94.7
91.1
N.A.
75.5
72.4
65.7
68
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
13.3
100
13.3
73.3
N.A.
33.3
6.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
33.3
100
26.6
86.6
N.A.
40
26.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.1
47.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
19
19
0
50
32
19
7
13
7
13
57
19
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
57
50
13
25
7
0
0
38
7
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
7
7
7
13
% I
% Lys:
19
7
0
7
13
19
13
25
32
13
75
69
7
57
63
% K
% Leu:
7
0
0
0
50
0
7
0
0
0
0
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
13
7
13
13
0
0
% P
% Gln:
0
0
7
0
0
0
44
0
7
0
0
0
0
0
0
% Q
% Arg:
57
0
7
50
0
19
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
7
13
44
0
0
7
0
7
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
13
0
0
0
0
7
0
0
7
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
7
7
7
0
0
50
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _