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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5F1
All Species:
22.12
Human Site:
Y116
Identified Species:
44.24
UniProt:
P24539
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24539
NP_001679.2
256
28909
Y116
M
V
Y
G
I
K
K
Y
G
P
F
V
A
D
F
Chimpanzee
Pan troglodytes
XP_513639
256
28920
Y116
M
V
Y
G
I
K
K
Y
G
P
F
V
A
D
F
Rhesus Macaque
Macaca mulatta
XP_001105535
256
28758
Y116
M
V
Y
G
I
K
K
Y
G
P
T
V
A
A
Y
Dog
Lupus familis
XP_537027
256
28788
Y116
L
I
Y
V
V
K
K
Y
G
A
S
I
G
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQQ7
256
28930
Y116
I
V
Y
V
I
K
K
Y
G
A
S
F
G
E
F
Rat
Rattus norvegicus
P19511
256
28850
Y116
I
V
Y
V
I
K
K
Y
G
A
S
I
G
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508128
288
32169
Y148
I
I
Y
G
I
K
K
Y
G
P
S
V
A
A
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001005960
252
28152
V116
V
K
K
F
G
P
S
V
A
A
F
A
D
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94516
243
27339
E117
I
A
K
W
A
D
G
E
I
D
K
I
E
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784941
249
28333
W122
L
G
P
G
I
A
E
W
A
D
K
K
R
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P05626
244
26992
A116
A
P
A
Y
K
D
F
A
D
A
R
M
K
K
V
Red Bread Mold
Neurospora crassa
Q7SE71
241
26258
E116
L
Y
K
K
W
A
D
E
Q
S
D
K
I
K
N
Conservation
Percent
Protein Identity:
100
99.6
91
85.1
N.A.
82.8
82
N.A.
69.7
N.A.
N.A.
56.6
N.A.
41.7
N.A.
N.A.
44.5
Protein Similarity:
100
99.6
96.4
93.3
N.A.
91.4
91.4
N.A.
80.2
N.A.
N.A.
72.2
N.A.
58.5
N.A.
N.A.
66.8
P-Site Identity:
100
100
80
40
N.A.
53.3
53.3
N.A.
73.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
73.3
N.A.
66.6
73.3
N.A.
86.6
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
23.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
9
17
0
9
17
42
0
9
34
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
9
0
9
17
9
0
9
17
0
% D
% Glu:
0
0
0
0
0
0
9
17
0
0
0
0
9
34
17
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
25
9
0
0
50
% F
% Gly:
0
9
0
42
9
0
9
0
59
0
0
0
25
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
17
0
0
59
0
0
0
9
0
0
25
9
0
0
% I
% Lys:
0
9
25
9
9
59
59
0
0
0
17
17
9
25
0
% K
% Leu:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
9
0
0
9
0
0
0
34
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
9
0
0
9
34
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
9
42
0
25
9
0
0
9
0
0
0
34
0
0
9
% V
% Trp:
0
0
0
9
9
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
9
59
9
0
0
0
59
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _