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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP5F1 All Species: 10.61
Human Site: Y187 Identified Species: 21.21
UniProt: P24539 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24539 NP_001679.2 256 28909 Y187 V T Y R E R L Y R V Y K E V K
Chimpanzee Pan troglodytes XP_513639 256 28920 Y187 V T Y R E R L Y R V Y K E V K
Rhesus Macaque Macaca mulatta XP_001105535 256 28758 Y187 V T Y R E R L Y R V Y K E V K
Dog Lupus familis XP_537027 256 28788 H187 L T Y R E R L H R V Y R E V K
Cat Felis silvestris
Mouse Mus musculus Q9CQQ7 256 28930 H187 V T Y R E R L H K A Y K E V K
Rat Rattus norvegicus P19511 256 28850 H187 V T Y R E R L H K A Y K E V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508128 288 32169 H219 V Y Y R E R L H R V Y T E V K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001005960 252 28152 H183 I N Y R E R L H M V T N E V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q94516 243 27339 M177 A A F R E R A M N V Y S E V K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784941 249 28333 Q186 I E Y R E R L Q Q V A Q A V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P05626 244 26992 V179 R F E L K Q K V E L A H E A K
Red Bread Mold Neurospora crassa Q7SE71 241 26258 T177 A Y E L E Q R T A L A A E A K
Conservation
Percent
Protein Identity: 100 99.6 91 85.1 N.A. 82.8 82 N.A. 69.7 N.A. N.A. 56.6 N.A. 41.7 N.A. N.A. 44.5
Protein Similarity: 100 99.6 96.4 93.3 N.A. 91.4 91.4 N.A. 80.2 N.A. N.A. 72.2 N.A. 58.5 N.A. N.A. 66.8
P-Site Identity: 100 100 100 80 N.A. 80 80 N.A. 80 N.A. N.A. 60 N.A. 53.3 N.A. N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 N.A. N.A. 73.3 N.A. 60 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 23.8
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 41.8
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 0 0 9 0 9 17 25 9 9 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 17 0 92 0 0 0 9 0 0 0 92 0 0 % E
% Phe: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 42 0 0 0 9 0 0 0 % H
% Ile: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 9 0 17 0 0 42 0 0 92 % K
% Leu: 9 0 0 17 0 0 75 0 0 17 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 9 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 17 0 9 9 0 0 9 0 0 9 % Q
% Arg: 9 0 0 84 0 84 9 0 42 0 0 9 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % S
% Thr: 0 50 0 0 0 0 0 9 0 0 9 9 0 0 0 % T
% Val: 50 0 0 0 0 0 0 9 0 67 0 0 0 84 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 75 0 0 0 0 25 0 0 67 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _