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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGFBP6 All Species: 4.55
Human Site: S152 Identified Species: 12.5
UniProt: P24592 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24592 NP_002169.1 240 25322 S152 T T P S Q P N S A G V Q D T E
Chimpanzee Pan troglodytes XP_509089 241 25403 S153 T T P S Q P N S A G V Q D T E
Rhesus Macaque Macaca mulatta XP_001112730 110 11146 L25 A A S P G G A L A R C P G C G
Dog Lupus familis XP_849343 240 25554 P152 T T S G R P N P G G V Q D A E
Cat Felis silvestris
Mouse Mus musculus P47880 238 25384 P149 T S A A P I R P N P V Q D S E
Rat Rattus norvegicus P35572 226 24175 P137 T S A A P I R P S P V Q D G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P49705 311 33520 G208 K K S R M P T G R T P C Q Q E
Frog Xenopus laevis Q90WV8 265 29976 P174 K V Q S P S T P E H S I E I D
Zebra Danio Brachydanio rerio Q9PTH3 276 30746 K176 D P K A P H A K Q S Q C Q Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 44.1 84.1 N.A. 69.5 66.2 N.A. N.A. 30.2 35.4 30.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 45.4 87 N.A. 78.3 73.3 N.A. N.A. 40.1 52 43.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 60 N.A. 33.3 33.3 N.A. N.A. 13.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 66.6 N.A. 53.3 53.3 N.A. N.A. 13.3 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 23 34 0 0 23 0 34 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 23 0 12 0 % C
% Asp: 12 0 0 0 0 0 0 0 0 0 0 0 56 0 12 % D
% Glu: 0 0 0 0 0 0 0 0 12 0 0 0 12 0 78 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 12 12 0 12 12 34 0 0 12 12 12 % G
% His: 0 0 0 0 0 12 0 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 23 0 0 0 0 0 12 0 12 0 % I
% Lys: 23 12 12 0 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 34 0 12 0 0 0 0 0 0 % N
% Pro: 0 12 23 12 45 45 0 45 0 23 12 12 0 0 0 % P
% Gln: 0 0 12 0 23 0 0 0 12 0 12 56 23 23 0 % Q
% Arg: 0 0 0 12 12 0 23 0 12 12 0 0 0 0 0 % R
% Ser: 0 23 34 34 0 12 0 23 12 12 12 0 0 12 0 % S
% Thr: 56 34 0 0 0 0 23 0 0 12 0 0 0 23 0 % T
% Val: 0 12 0 0 0 0 0 0 0 0 56 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _