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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAT1
All Species:
6.06
Human Site:
S16
Identified Species:
10.26
UniProt:
P24752
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24752
NP_000010.1
427
45200
S16
R
S
G
A
R
S
R
S
P
L
L
R
R
L
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103928
427
45080
S16
R
G
G
A
R
S
R
S
P
L
L
R
R
L
V
Dog
Lupus familis
XP_546539
433
45733
A22
G
V
V
E
N
A
R
A
R
L
V
R
R
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZT1
424
44798
R17
V
V
R
R
P
L
L
R
G
L
L
Q
E
V
R
Rat
Rattus norvegicus
P17764
424
44676
R17
V
V
R
R
P
L
L
R
G
L
L
Q
E
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508601
416
43920
R14
P
G
L
S
L
P
G
R
L
L
R
D
L
K
Y
Chicken
Gallus gallus
XP_417162
421
44071
A14
L
G
R
R
R
A
A
A
G
L
L
R
A
L
K
Frog
Xenopus laevis
Q6GN02
420
44054
H14
R
T
A
A
R
L
S
H
S
T
R
A
L
H
Y
Zebra Danio
Brachydanio rerio
Q6AZA0
420
44324
R15
S
T
R
S
Q
L
C
R
H
L
A
H
K
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572414
410
43452
A14
Q
A
T
R
R
W
S
A
H
R
N
Y
S
S
K
Honey Bee
Apis mellifera
XP_001121974
405
43669
K16
R
L
Y
S
S
K
V
K
L
N
D
V
V
I
V
Nematode Worm
Caenorhab. elegans
NP_495455
407
42424
S20
I
T
T
S
A
A
L
S
N
K
H
A
F
I
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIK7
415
43273
D14
D
D
S
L
Q
P
R
D
V
C
V
V
G
V
A
Baker's Yeast
Sacchar. cerevisiae
P41338
398
41710
G16
S
T
A
R
T
P
I
G
S
F
Q
G
S
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
85.2
N.A.
84.3
84.5
N.A.
77.5
77.2
74.7
77.2
N.A.
62.7
63
51.9
N.A.
Protein Similarity:
100
N.A.
99
91.4
N.A.
91.8
92
N.A.
86.1
85.9
86.4
86.6
N.A.
76.5
76.3
68.6
N.A.
P-Site Identity:
100
N.A.
93.3
26.6
N.A.
13.3
13.3
N.A.
6.6
33.3
20
6.6
N.A.
6.6
13.3
13.3
N.A.
P-Site Similarity:
100
N.A.
93.3
53.3
N.A.
26.6
26.6
N.A.
13.3
46.6
26.6
40
N.A.
26.6
26.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.9
42.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66
61.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
22
8
22
8
22
0
0
8
15
8
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
8
% C
% Asp:
8
8
0
0
0
0
0
8
0
0
8
8
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
8
22
15
0
0
0
8
8
22
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
15
0
8
8
0
8
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
0
15
0
% I
% Lys:
0
0
0
0
0
8
0
8
0
8
0
0
8
8
15
% K
% Leu:
8
8
8
8
8
29
22
0
15
58
36
0
15
29
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
8
8
0
0
0
0
% N
% Pro:
8
0
0
0
15
22
0
0
15
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
15
0
0
0
0
0
8
15
0
0
0
% Q
% Arg:
29
0
29
36
36
0
29
29
8
8
15
29
22
0
15
% R
% Ser:
15
8
8
29
8
15
15
22
15
0
0
0
15
8
8
% S
% Thr:
0
29
15
0
8
0
0
0
0
8
0
0
0
0
0
% T
% Val:
15
22
8
0
0
0
8
0
8
0
15
15
8
29
29
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _