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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNASE1
All Species:
28.18
Human Site:
S65
Identified Species:
77.5
UniProt:
P24855
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24855
NP_005214.2
282
31434
S65
L
V
Q
E
V
R
D
S
H
L
T
A
V
G
K
Chimpanzee
Pan troglodytes
XP_001168176
282
31357
S65
L
V
Q
E
V
R
D
S
H
L
T
A
V
G
K
Rhesus Macaque
Macaca mulatta
XP_001095110
282
31415
S65
L
V
Q
E
V
R
D
S
H
L
T
A
V
G
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P49183
284
32009
S65
V
I
Q
E
V
R
D
S
H
L
V
A
V
G
K
Rat
Rattus norvegicus
P21704
284
32046
T65
V
V
Q
E
V
R
D
T
H
L
V
A
V
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506333
315
35674
S98
L
I
Q
E
V
R
D
S
R
L
T
A
V
G
K
Chicken
Gallus gallus
Q9YGI5
282
31382
A63
L
V
Q
E
V
R
D
A
D
L
S
S
V
K
K
Frog
Xenopus laevis
NP_001079750
295
34205
S60
L
L
M
E
I
K
D
S
S
N
T
V
I
R
L
Zebra Danio
Brachydanio rerio
NP_001002674
278
30996
S62
L
I
Q
E
V
R
D
S
D
L
S
A
T
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.6
N.A.
N.A.
79.2
77.4
N.A.
57.4
57
44.4
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
96.4
N.A.
N.A.
87.6
88
N.A.
71.1
70.5
62
73.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
80
80
N.A.
86.6
66.6
33.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
86.6
60
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
78
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
100
0
23
0
0
0
0
0
0
% D
% Glu:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% G
% His:
0
0
0
0
0
0
0
0
56
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
12
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
89
% K
% Leu:
78
12
0
0
0
0
0
0
0
89
0
0
0
0
12
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
89
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
89
0
0
12
0
0
0
0
12
0
% R
% Ser:
0
0
0
0
0
0
0
78
12
0
23
12
0
12
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
56
0
12
0
0
% T
% Val:
23
56
0
0
89
0
0
0
0
0
23
12
78
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _