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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNASE1 All Species: 34.24
Human Site: S97 Identified Species: 94.17
UniProt: P24855 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24855 NP_005214.2 282 31434 S97 S E P L G R N S Y K E R Y L F
Chimpanzee Pan troglodytes XP_001168176 282 31357 S97 S E P L G R N S Y K E R Y L F
Rhesus Macaque Macaca mulatta XP_001095110 282 31415 S97 S E P L G R N S Y K E R Y L F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P49183 284 32009 S97 S E P L G R K S Y K E Q Y L F
Rat Rattus norvegicus P21704 284 32046 S97 S E P L G R K S Y K E Q Y L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506333 315 35674 S130 S E P L G R G S Y K E Q Y L F
Chicken Gallus gallus Q9YGI5 282 31382 S95 S I P L G R N S Y K E Q Y V F
Frog Xenopus laevis NP_001079750 295 34205 S94 S Q R L G R K S Y K E Q Y G F
Zebra Danio Brachydanio rerio NP_001002674 278 30996 T95 S E P L G R N T Y K E R Y L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.6 N.A. N.A. 79.2 77.4 N.A. 57.4 57 44.4 56.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 96.4 N.A. N.A. 87.6 88 N.A. 71.1 70.5 62 73.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 86.6 86.6 N.A. 86.6 80 66.6 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 93.3 93.3 80 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 78 0 0 0 0 0 0 0 0 100 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % F
% Gly: 0 0 0 0 100 0 12 0 0 0 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 34 0 0 100 0 0 0 0 0 % K
% Leu: 0 0 0 100 0 0 0 0 0 0 0 0 0 78 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 0 0 0 0 0 0 0 0 0 56 0 0 0 % Q
% Arg: 0 0 12 0 0 100 0 0 0 0 0 45 0 0 0 % R
% Ser: 100 0 0 0 0 0 0 89 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 100 0 0 0 100 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _