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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNC All Species: 43.94
Human Site: Y122 Identified Species: 69.05
UniProt: P24863 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24863 NP_005181.2 283 33243 Y122 V L K T R F S Y A F P K E F P
Chimpanzee Pan troglodytes XP_001140526 282 33121 Y122 V L K T R F S Y A F P K E F P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_854102 303 35206 Y142 V L K T R F S Y A F P K E F P
Cat Felis silvestris
Mouse Mus musculus Q62447 283 33174 Y122 V L K T R F S Y A F P K E F P
Rat Rattus norvegicus P39947 278 32495 Y117 V L K T R F S Y A S P K E F P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506806 405 46059 Y244 V L K T R F S Y A F P K E F P
Chicken Gallus gallus P55168 283 33240 Y122 V L K T R F S Y A F P K E F P
Frog Xenopus laevis Q4KLA0 283 33159 Y122 V L K T R F S Y A F P K E F P
Zebra Danio Brachydanio rerio NP_956245 283 33167 Y122 V L K T R F S Y A F P K E F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25008 267 31274 Y122 A I K T K F S Y A Y A Q E F P
Honey Bee Apis mellifera XP_395475 267 31267 Y122 V V K N K F N Y A Y S Q E F P
Nematode Worm Caenorhab. elegans Q9TYP2 302 34995 V131 V L P K R W G V T F E T T S T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJK7 253 29826 L114 L V F Y M K K L Y A D E K F R
Baker's Yeast Sacchar. cerevisiae P47821 323 37772 D156 W P E F I P P D P T K V T E F
Red Bread Mold Neurospora crassa Q9HE63 345 38453 Q129 W P T D F Q S Q T E V A R I G
Conservation
Percent
Protein Identity: 100 93.6 N.A. 93 N.A. 98.9 96.8 N.A. 68.8 99.6 97.8 93.9 N.A. 68.1 65.3 37.4 N.A.
Protein Similarity: 100 93.9 N.A. 93.4 N.A. 99.2 97.1 N.A. 69.1 100 99.2 98.2 N.A. 81.2 78 58.6 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 100 100 100 100 N.A. 60 53.3 26.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 100 100 100 100 N.A. 86.6 86.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36 22.2 24.9
Protein Similarity: N.A. N.A. N.A. 57.2 42.4 42.9
P-Site Identity: N.A. N.A. N.A. 6.6 0 6.6
P-Site Similarity: N.A. N.A. N.A. 33.3 6.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 0 0 74 7 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 7 0 0 7 0 0 0 0 % D
% Glu: 0 0 7 0 0 0 0 0 0 7 7 7 74 7 0 % E
% Phe: 0 0 7 7 7 74 0 0 0 60 0 0 0 80 7 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 7 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 0 0 74 7 14 7 7 0 0 0 7 60 7 0 0 % K
% Leu: 7 67 0 0 0 0 0 7 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 14 7 0 0 7 7 0 7 0 60 0 0 0 74 % P
% Gln: 0 0 0 0 0 7 0 7 0 0 0 14 0 0 0 % Q
% Arg: 0 0 0 0 67 0 0 0 0 0 0 0 7 0 7 % R
% Ser: 0 0 0 0 0 0 74 0 0 7 7 0 0 7 0 % S
% Thr: 0 0 7 67 0 0 0 0 14 7 0 7 14 0 7 % T
% Val: 74 14 0 0 0 0 0 7 0 0 7 7 0 0 0 % V
% Trp: 14 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 74 7 14 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _