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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
26.06
Human Site:
S399
Identified Species:
44.1
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S399
G
L
L
T
P
P
Q
S
G
K
K
Q
S
S
G
Chimpanzee
Pan troglodytes
XP_512559
393
44800
Q381
S
G
L
L
T
P
P
Q
S
G
K
K
Q
S
S
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S399
G
L
L
T
P
P
Q
S
S
K
K
Q
S
S
E
Dog
Lupus familis
XP_541724
456
51105
S445
G
V
L
T
P
P
Q
S
S
K
K
Q
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
S397
V
V
L
T
P
P
P
S
S
K
K
Q
S
S
E
Rat
Rattus norvegicus
P39949
411
47463
S400
G
V
L
T
P
P
H
S
S
K
K
Q
S
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
N388
G
Q
L
S
P
V
C
N
G
G
I
M
T
P
P
Chicken
Gallus gallus
P49707
407
46720
S396
G
V
L
T
P
P
Q
S
S
K
K
Q
P
A
G
Frog
Xenopus laevis
Q91780
408
47153
S398
G
V
L
T
P
P
Q
S
N
K
K
Q
K
S
D
Zebra Danio
Brachydanio rerio
P47794
410
46612
P400
T
G
V
L
T
P
P
P
S
S
E
K
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
L663
S
H
K
P
D
E
Y
L
G
D
E
G
D
E
T
Honey Bee
Apis mellifera
XP_394802
457
51232
S426
N
V
E
S
G
R
Q
S
P
N
E
S
G
L
L
Nematode Worm
Caenorhab. elegans
O01501
524
60567
S505
S
M
E
P
I
V
K
S
E
R
E
R
I
Q
H
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
Q414
P
G
V
L
T
P
P
Q
S
D
K
K
T
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
26.6
86.6
86.6
N.A.
66.6
73.3
N.A.
26.6
73.3
73.3
6.6
N.A.
6.6
13.3
6.6
13.3
P-Site Similarity:
100
33.3
86.6
93.3
N.A.
73.3
80
N.A.
46.6
86.6
80
26.6
N.A.
13.3
33.3
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
15
0
0
8
0
8
% D
% Glu:
0
0
15
0
0
8
0
0
8
0
29
0
0
15
22
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
22
0
0
8
0
0
0
22
15
0
8
8
0
22
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
50
65
22
8
8
8
% K
% Leu:
0
15
65
22
0
0
0
8
0
0
0
0
0
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% N
% Pro:
8
0
0
15
58
72
29
8
8
0
0
0
15
8
8
% P
% Gln:
0
8
0
0
0
0
43
15
0
0
0
50
8
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% R
% Ser:
22
0
0
15
0
0
0
65
58
8
0
8
36
50
15
% S
% Thr:
8
0
0
50
22
0
0
0
0
0
0
0
15
0
8
% T
% Val:
8
43
15
0
0
15
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _