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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNE1 All Species: 22.12
Human Site: T126 Identified Species: 37.44
UniProt: P24864 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24864 NP_001229.1 410 47077 T126 I M L N K E K T Y L R D Q H F
Chimpanzee Pan troglodytes XP_512559 393 44800 Q118 R D Q H F L E Q H P L L Q P K
Rhesus Macaque Macaca mulatta XP_001084995 410 47103 T126 I M L N K E K T Y L R D Q H F
Dog Lupus familis XP_541724 456 51105 T172 I M L N K E K T Y L R D K H F
Cat Felis silvestris
Mouse Mus musculus Q61457 408 46968 T124 I M L N K E K T Y L R D E H F
Rat Rattus norvegicus P39949 411 47463 T127 I M L N K E K T Y L R D E H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507249 405 46635 K124 N L L N K E T K Y V H D K H F
Chicken Gallus gallus P49707 407 46720 T123 N M I N K E E T Y V R D K L Y
Frog Xenopus laevis Q91780 408 47153 I125 N M L N K D R I Y L R D K N F
Zebra Danio Brachydanio rerio P47794 410 46612 L128 N L L G K D K L Y L R D T R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54733 709 77202 Q341 L M C H R D E Q D S R L R S I
Honey Bee Apis mellifera XP_394802 457 51232 K132 L M C L G D Q K T I T Q R N P
Nematode Worm Caenorhab. elegans O01501 524 60567 I243 L M V K R D E I P R A T R F L
Sea Urchin Strong. purpuratus XP_785047 424 48468 A136 T I M T R K E A L C P R K H D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 98.2 73.9 N.A. 78.7 79.5 N.A. 49 71.9 60.2 58.2 N.A. 28.2 38.2 24.2 44.5
Protein Similarity: 100 95.3 98.5 81.1 N.A. 88.7 90 N.A. 66.5 85.1 76.8 73.9 N.A. 39.6 55.1 41.4 60.8
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 93.3 N.A. 53.3 53.3 60 46.6 N.A. 13.3 6.6 6.6 6.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 73.3 86.6 86.6 60 N.A. 53.3 46.6 46.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % A
% Cys: 0 0 15 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 36 0 0 8 0 0 65 0 0 8 % D
% Glu: 0 0 0 0 0 50 36 0 0 0 0 0 15 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 50 % F
% Gly: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 15 0 0 0 0 8 0 8 0 0 50 0 % H
% Ile: 36 8 8 0 0 0 0 15 0 8 0 0 0 0 8 % I
% Lys: 0 0 0 8 65 8 43 15 0 0 0 0 36 0 8 % K
% Leu: 22 15 58 8 0 8 0 8 8 50 8 15 0 8 8 % L
% Met: 0 72 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 29 0 0 58 0 0 0 0 0 0 0 0 0 15 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 8 8 0 0 8 8 % P
% Gln: 0 0 8 0 0 0 8 15 0 0 0 8 22 0 0 % Q
% Arg: 8 0 0 0 22 0 8 0 0 8 65 8 22 8 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % S
% Thr: 8 0 0 8 0 0 8 43 8 0 8 8 8 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 15 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 65 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _