KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
16.67
Human Site:
T52
Identified Species:
28.21
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
T52
E
M
A
K
I
D
R
T
A
R
D
Q
C
G
S
Chimpanzee
Pan troglodytes
XP_512559
393
44800
N46
C
G
S
Q
P
W
D
N
N
A
V
C
A
D
P
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
T52
E
M
A
K
I
D
R
T
A
R
D
Q
C
G
S
Dog
Lupus familis
XP_541724
456
51105
T98
E
V
A
K
I
D
R
T
A
R
G
Q
C
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
T49
E
I
A
K
I
D
K
T
V
K
S
E
D
S
S
Rat
Rattus norvegicus
P39949
411
47463
T52
E
I
A
K
I
D
K
T
V
K
S
Q
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
R50
K
D
D
K
V
S
K
R
H
Q
Y
E
I
R
S
Chicken
Gallus gallus
P49707
407
46720
M49
E
E
I
A
K
I
E
M
S
R
K
K
Q
Y
E
Frog
Xenopus laevis
Q91780
408
47153
K51
D
S
L
E
M
T
K
K
K
Q
Y
Q
D
R
G
Zebra Danio
Brachydanio rerio
P47794
410
46612
A54
M
T
R
K
K
Q
C
A
S
Q
A
C
W
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
A267
Y
S
S
T
I
S
P
A
S
S
G
C
S
Q
Q
Honey Bee
Apis mellifera
XP_394802
457
51232
S54
I
P
A
L
S
H
V
S
Y
T
E
S
C
H
T
Nematode Worm
Caenorhab. elegans
O01501
524
60567
L142
K
S
S
S
S
D
N
L
A
E
S
E
E
S
H
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
W63
Q
F
T
I
E
N
R
W
V
P
I
S
E
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
0
100
80
N.A.
46.6
53.3
N.A.
13.3
13.3
6.6
6.6
N.A.
6.6
13.3
13.3
13.3
P-Site Similarity:
100
13.3
100
86.6
N.A.
73.3
73.3
N.A.
46.6
26.6
40
20
N.A.
20
33.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
43
8
0
0
0
15
29
8
8
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
8
0
0
0
0
22
29
0
0
% C
% Asp:
8
8
8
0
0
43
8
0
0
0
15
0
22
8
0
% D
% Glu:
43
8
0
8
8
0
8
0
0
8
8
22
15
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
15
0
0
22
15
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
8
8
% H
% Ile:
8
15
8
8
43
8
0
0
0
0
8
0
8
0
0
% I
% Lys:
15
0
0
50
15
0
29
8
8
15
8
8
0
0
0
% K
% Leu:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
8
15
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
8
8
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
8
0
8
0
0
8
0
0
0
0
15
% P
% Gln:
8
0
0
8
0
8
0
0
0
22
0
36
8
8
8
% Q
% Arg:
0
0
8
0
0
0
29
8
0
29
0
0
0
15
0
% R
% Ser:
0
22
22
8
15
15
0
8
22
8
22
15
8
29
43
% S
% Thr:
0
8
8
8
0
8
0
36
0
8
0
0
0
0
8
% T
% Val:
0
8
0
0
8
0
8
0
22
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
8
0
15
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _