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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2F1
All Species:
24.85
Human Site:
Y348
Identified Species:
78.1
UniProt:
P24903
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24903
NP_000765.2
491
55501
Y348
K
D
R
A
A
M
P
Y
T
D
A
V
I
H
E
Chimpanzee
Pan troglodytes
XP_001139965
375
42213
M249
R
F
A
D
I
I
P
M
N
L
P
H
R
V
T
Rhesus Macaque
Macaca mulatta
Q6GUQ4
493
56626
Y349
K
D
R
Q
E
M
P
Y
M
D
A
V
V
H
E
Dog
Lupus familis
XP_855301
582
65240
Y423
E
D
R
A
A
M
P
Y
T
D
A
V
I
H
E
Cat
Felis silvestris
Mouse
Mus musculus
P33267
491
55930
Y348
E
D
R
T
S
M
P
Y
T
D
A
V
I
H
E
Rat
Rattus norvegicus
O35293
491
55927
Y348
E
D
R
A
S
M
P
Y
T
D
A
V
I
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001001752
494
55718
Y351
A
D
R
T
Q
M
P
Y
T
D
A
V
V
H
E
Frog
Xenopus laevis
NP_001085245
496
56377
Y353
E
D
R
S
R
M
P
Y
T
D
A
V
I
H
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
48
75
N.A.
81.8
83
N.A.
N.A.
52.4
51
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.5
70.1
79.7
N.A.
90.8
91.6
N.A.
N.A.
72.4
70.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
73.3
93.3
N.A.
80
86.6
N.A.
N.A.
73.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
80
100
N.A.
93.3
100
N.A.
N.A.
80
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
38
25
0
0
0
0
0
88
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
88
0
13
0
0
0
0
0
88
0
0
0
0
0
% D
% Glu:
50
0
0
0
13
0
0
0
0
0
0
0
0
0
88
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
88
0
% H
% Ile:
0
0
0
0
13
13
0
0
0
0
0
0
63
0
0
% I
% Lys:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
88
0
13
13
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
100
0
0
0
13
0
0
0
0
% P
% Gln:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
88
0
13
0
0
0
0
0
0
0
13
0
0
% R
% Ser:
0
0
0
13
25
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
25
0
0
0
0
75
0
0
0
0
0
13
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
88
25
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
88
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _