KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2
All Species:
42.12
Human Site:
S239
Identified Species:
57.92
UniProt:
P24941
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24941
NP_001789.2
298
33930
S239
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Chimpanzee
Pan troglodytes
XP_523720
325
36841
S259
Q
L
P
D
Y
K
G
S
F
P
K
W
T
R
K
Rhesus Macaque
Macaca mulatta
XP_001113345
298
33812
S239
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Dog
Lupus familis
XP_856049
298
33839
S239
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97377
346
38960
S287
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Rat
Rattus norvegicus
Q63699
298
33869
S239
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
T240
S
L
Q
D
Y
K
N
T
F
P
K
W
K
P
G
Frog
Xenopus laevis
P23437
297
33852
T239
T
M
P
D
Y
K
S
T
F
P
K
W
I
R
Q
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
S239
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23573
314
35870
K242
Q
L
P
D
F
K
T
K
F
P
R
W
E
G
T
Honey Bee
Apis mellifera
XP_393450
299
34033
M238
Q
L
R
D
Y
T
S
M
F
P
R
W
E
P
R
Nematode Worm
Caenorhab. elegans
P34556
332
38277
T258
S
L
P
D
Y
K
A
T
F
P
K
W
R
E
N
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
S239
S
L
P
D
Y
K
T
S
F
P
R
W
T
P
Q
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
S233
D
T
W
P
G
V
T
S
L
P
D
F
K
S
A
Maize
Zea mays
P23111
294
33816
C233
Q
S
W
P
G
V
S
C
L
P
D
F
K
T
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
S233
D
T
W
R
G
V
T
S
L
P
D
Y
K
S
A
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
V240
E
A
I
W
P
D
I
V
Y
L
P
D
F
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.8
99.6
98.9
N.A.
85.2
98.6
N.A.
N.A.
65.3
88.9
90.2
N.A.
62.7
69.9
56.9
75.9
Protein Similarity:
100
79.6
99.6
99.6
N.A.
85.8
99.6
N.A.
N.A.
77.8
94.9
94.9
N.A.
74.8
82.2
69.8
88.6
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
N.A.
53.3
73.3
100
N.A.
40
33.3
60
66.6
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
N.A.
66.6
86.6
100
N.A.
60
53.3
73.3
80
Percent
Protein Identity:
66.4
66.7
N.A.
67.1
62.4
N.A.
Protein Similarity:
83.2
82.2
N.A.
81.5
79.1
N.A.
P-Site Identity:
13.3
6.6
N.A.
13.3
0
N.A.
P-Site Similarity:
20
13.3
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
6
0
0
0
0
0
36
0
18
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
77
0
6
0
0
0
0
18
6
0
0
0
% D
% Glu:
6
0
0
0
0
0
0
0
0
0
0
0
12
6
0
% E
% Phe:
0
0
0
0
6
0
0
0
77
0
0
12
6
0
0
% F
% Gly:
0
0
0
0
18
0
6
0
0
0
0
0
0
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
0
0
6
0
0
0
0
0
6
0
0
% I
% Lys:
0
0
0
0
0
71
0
6
0
0
59
0
24
6
6
% K
% Leu:
0
36
0
0
0
0
0
0
18
6
0
0
0
0
0
% L
% Met:
0
42
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
6
% N
% Pro:
0
0
65
12
6
0
36
0
0
95
6
0
0
18
6
% P
% Gln:
24
0
6
0
0
0
0
0
0
0
0
0
0
0
48
% Q
% Arg:
0
0
6
6
0
0
0
0
0
0
18
0
6
48
6
% R
% Ser:
53
6
0
0
0
0
18
59
0
0
0
0
0
12
0
% S
% Thr:
6
12
0
0
0
6
24
18
0
0
0
0
12
6
6
% T
% Val:
0
0
0
0
0
18
0
6
0
0
0
0
0
0
0
% V
% Trp:
0
0
18
6
0
0
0
0
0
0
0
77
0
0
0
% W
% Tyr:
0
0
0
0
71
0
0
0
6
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _