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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH2
All Species:
18.18
Human Site:
S160
Identified Species:
36.36
UniProt:
P25021
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25021
NP_071640.1
359
40098
S160
S
I
H
L
G
W
N
S
R
N
E
T
S
K
G
Chimpanzee
Pan troglodytes
XP_001162258
428
48268
N162
L
P
I
M
Q
G
W
N
N
I
G
I
I
D
L
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
R175
P
I
Q
M
H
W
Y
R
A
T
H
Q
E
A
I
Dog
Lupus familis
XP_546225
359
40183
S160
S
I
H
L
G
W
N
S
R
N
E
T
S
S
F
Cat
Felis silvestris
Mouse
Mus musculus
P97292
358
40361
S160
S
I
H
L
G
W
N
S
R
N
G
T
R
G
G
Rat
Rattus norvegicus
P25102
358
40235
S160
S
I
H
L
G
W
N
S
R
N
G
T
R
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425208
351
39363
T156
N
G
T
M
V
Q
N
T
T
P
N
C
T
R
E
Frog
Xenopus laevis
O42574
385
43291
R177
P
I
M
M
H
W
W
R
D
T
G
D
P
L
A
Zebra Danio
Brachydanio rerio
NP_001038803
410
45665
T187
P
I
H
L
G
W
N
T
R
D
L
S
V
Q
N
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
R181
P
V
Q
L
N
W
H
R
A
D
N
N
S
S
A
Fruit Fly
Dros. melanogaster
Q9VCZ3
508
56837
T249
P
I
C
S
G
W
Y
T
T
T
E
N
Y
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792332
363
40947
V154
R
L
T
R
R
K
A
V
I
T
L
I
I
V
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
31
86.9
N.A.
84.9
86
N.A.
N.A.
57
33.7
45.1
29.5
28.9
N.A.
N.A.
40.2
Protein Similarity:
100
50
50.3
92.7
N.A.
90.2
89.9
N.A.
N.A.
69.3
51.6
60.7
48.6
43.1
N.A.
N.A.
57.3
P-Site Identity:
100
0
13.3
86.6
N.A.
80
80
N.A.
N.A.
6.6
13.3
46.6
20
33.3
N.A.
N.A.
0
P-Site Similarity:
100
13.3
20
86.6
N.A.
80
80
N.A.
N.A.
40
20
73.3
40
40
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
17
0
0
0
0
9
17
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
17
0
9
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
25
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
9
0
0
50
9
0
0
0
0
34
0
0
17
25
% G
% His:
0
0
42
0
17
0
9
0
0
0
9
0
0
0
0
% H
% Ile:
0
67
9
0
0
0
0
0
9
9
0
17
17
0
9
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
0
% K
% Leu:
9
9
0
50
0
0
0
0
0
0
17
0
0
9
9
% L
% Met:
0
0
9
34
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
50
9
9
34
17
17
0
0
9
% N
% Pro:
42
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% P
% Gln:
0
0
17
0
9
9
0
0
0
0
0
9
0
9
0
% Q
% Arg:
9
0
0
9
9
0
0
25
42
0
0
0
17
9
0
% R
% Ser:
34
0
0
9
0
0
0
34
0
0
0
9
25
17
0
% S
% Thr:
0
0
17
0
0
0
0
25
17
34
0
34
9
0
0
% T
% Val:
0
9
0
0
9
0
0
9
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
75
17
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _