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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH2
All Species:
1.52
Human Site:
S172
Identified Species:
3.03
UniProt:
P25021
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25021
NP_071640.1
359
40098
S172
S
K
G
N
H
T
T
S
K
C
K
V
Q
V
N
Chimpanzee
Pan troglodytes
XP_001162258
428
48268
K174
I
D
L
I
E
K
R
K
F
N
Q
N
S
N
S
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
K187
E
A
I
N
C
Y
A
K
E
T
C
C
D
F
F
Dog
Lupus familis
XP_546225
359
40183
P172
S
S
F
N
H
T
I
P
K
C
K
V
Q
V
N
Cat
Felis silvestris
Mouse
Mus musculus
P97292
358
40361
K172
R
G
G
N
D
T
F
K
C
K
V
Q
V
N
E
Rat
Rattus norvegicus
P25102
358
40235
K172
R
G
G
N
D
T
F
K
C
K
V
Q
V
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425208
351
39363
V168
T
R
E
C
K
L
E
V
N
S
V
Y
G
L
V
Frog
Xenopus laevis
O42574
385
43291
E189
P
L
A
M
K
C
Y
E
D
P
G
C
C
D
F
Zebra Danio
Brachydanio rerio
NP_001038803
410
45665
D199
V
Q
N
I
R
E
G
D
H
A
R
D
C
R
F
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
D193
S
S
A
H
E
Q
G
D
C
N
A
S
L
N
R
Fruit Fly
Dros. melanogaster
Q9VCZ3
508
56837
P261
Y
K
Y
L
K
S
N
P
H
I
C
E
F
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792332
363
40947
S166
I
V
W
A
V
S
I
S
I
S
F
L
P
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
31
86.9
N.A.
84.9
86
N.A.
N.A.
57
33.7
45.1
29.5
28.9
N.A.
N.A.
40.2
Protein Similarity:
100
50
50.3
92.7
N.A.
90.2
89.9
N.A.
N.A.
69.3
51.6
60.7
48.6
43.1
N.A.
N.A.
57.3
P-Site Identity:
100
0
6.6
73.3
N.A.
20
20
N.A.
N.A.
0
0
0
6.6
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
13.3
73.3
N.A.
20
20
N.A.
N.A.
20
0
13.3
13.3
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
9
0
0
9
0
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
9
9
9
0
0
25
17
17
17
17
0
0
% C
% Asp:
0
9
0
0
17
0
0
17
9
0
0
9
9
9
0
% D
% Glu:
9
0
9
0
17
9
9
9
9
0
0
9
0
0
17
% E
% Phe:
0
0
9
0
0
0
17
0
9
0
9
0
9
9
25
% F
% Gly:
0
17
25
0
0
0
17
0
0
0
9
0
9
0
0
% G
% His:
0
0
0
9
17
0
0
0
17
0
0
0
0
0
9
% H
% Ile:
17
0
9
17
0
0
17
0
9
9
0
0
0
0
0
% I
% Lys:
0
17
0
0
25
9
0
34
17
17
17
0
0
9
0
% K
% Leu:
0
9
9
9
0
9
0
0
0
0
0
9
9
17
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
42
0
0
9
0
9
17
0
9
0
34
17
% N
% Pro:
9
0
0
0
0
0
0
17
0
9
0
0
9
0
0
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
9
17
17
0
0
% Q
% Arg:
17
9
0
0
9
0
9
0
0
0
9
0
0
9
9
% R
% Ser:
25
17
0
0
0
17
0
17
0
17
0
9
9
0
9
% S
% Thr:
9
0
0
0
0
34
9
0
0
9
0
0
0
0
0
% T
% Val:
9
9
0
0
9
0
0
9
0
0
25
17
17
17
17
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
9
9
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _