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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HRH2 All Species: 10.91
Human Site: S9 Identified Species: 21.82
UniProt: P25021 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25021 NP_071640.1 359 40098 S9 A P N G T A S S F C L D S T A
Chimpanzee Pan troglodytes XP_001162258 428 48268 S10 K L D A N V S S E E G F G S V
Rhesus Macaque Macaca mulatta Q28509 415 46453 V24 S H A P D H D V T Q E R D E A
Dog Lupus familis XP_546225 359 40183 S9 I S N G T G S S F C L D S P P
Cat Felis silvestris
Mouse Mus musculus P97292 358 40361 S9 E P N G T V H S C C L D S I A
Rat Rattus norvegicus P25102 358 40235 S9 E P N G T V H S C C L D S M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425208 351 39363 V9 D F P L Q L L V G S C L A L L
Frog Xenopus laevis O42574 385 43291 P26 T V P S P M H P L P E L T H Q
Zebra Danio Brachydanio rerio NP_001038803 410 45665 K36 E Q K E R Y N K S A T D R M T
Tiger Blowfish Takifugu rubipres P53454 463 51077 P30 V T A A E D V P A P V G G V S
Fruit Fly Dros. melanogaster Q9VCZ3 508 56837 L104 D A D G S S H L A L V F V K C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792332 363 40947 T9 E E V D S N Y T L I Y Y D N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.8 31 86.9 N.A. 84.9 86 N.A. N.A. 57 33.7 45.1 29.5 28.9 N.A. N.A. 40.2
Protein Similarity: 100 50 50.3 92.7 N.A. 90.2 89.9 N.A. N.A. 69.3 51.6 60.7 48.6 43.1 N.A. N.A. 57.3
P-Site Identity: 100 13.3 6.6 66.6 N.A. 66.6 66.6 N.A. N.A. 0 0 6.6 0 6.6 N.A. N.A. 0
P-Site Similarity: 100 26.6 13.3 66.6 N.A. 66.6 66.6 N.A. N.A. 6.6 6.6 13.3 13.3 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 17 17 0 9 0 0 17 9 0 0 9 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 17 34 9 0 0 0 9 % C
% Asp: 17 0 17 9 9 9 9 0 0 0 0 42 17 0 9 % D
% Glu: 34 9 0 9 9 0 0 0 9 9 17 0 0 9 0 % E
% Phe: 0 9 0 0 0 0 0 0 17 0 0 17 0 0 0 % F
% Gly: 0 0 0 42 0 9 0 0 9 0 9 9 17 0 0 % G
% His: 0 9 0 0 0 9 34 0 0 0 0 0 0 9 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % I
% Lys: 9 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % K
% Leu: 0 9 0 9 0 9 9 9 17 9 34 17 0 9 9 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 17 0 % M
% Asn: 0 0 34 0 9 9 9 0 0 0 0 0 0 9 0 % N
% Pro: 0 25 17 9 9 0 0 17 0 17 0 0 0 9 9 % P
% Gln: 0 9 0 0 9 0 0 0 0 9 0 0 0 0 9 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 9 9 0 0 % R
% Ser: 9 9 0 9 17 9 25 42 9 9 0 0 34 9 9 % S
% Thr: 9 9 0 0 34 0 0 9 9 0 9 0 9 9 9 % T
% Val: 9 9 9 0 0 25 9 17 0 0 17 0 9 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 9 0 0 0 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _