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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HRH2 All Species: 13.03
Human Site: T315 Identified Species: 26.06
UniProt: P25021 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25021 NP_071640.1 359 40098 T315 A N R N S H K T S L R S N A S
Chimpanzee Pan troglodytes XP_001162258 428 48268 I339 E R Y R R P S I L G Q T V P C
Rhesus Macaque Macaca mulatta Q28509 415 46453 N352 S S L K A C G N G Y S S N S N
Dog Lupus familis XP_546225 359 40183 T315 A S H N A Q E T S L R S N S S
Cat Felis silvestris
Mouse Mus musculus P97292 358 40361 T314 A S H N S H K T S L R L N N S
Rat Rattus norvegicus P25102 358 40235 T314 A S H N S H K T S L R L N N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425208 351 39363 L310 T G D P K S S L Q K G Q P R G
Frog Xenopus laevis O42574 385 43291 Y325 S A F N P I I Y C R S P D F R
Zebra Danio Brachydanio rerio NP_001038803 410 45665 I352 R C K T E T T I P I A A T A A
Tiger Blowfish Takifugu rubipres P53454 463 51077 A361 C S S S A V Q A V D F S N E L
Fruit Fly Dros. melanogaster Q9VCZ3 508 56837 R431 P Y A F Y F C R R G R G R D D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792332 363 40947 T306 F R R R E S N T Y I S H L E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.8 31 86.9 N.A. 84.9 86 N.A. N.A. 57 33.7 45.1 29.5 28.9 N.A. N.A. 40.2
Protein Similarity: 100 50 50.3 92.7 N.A. 90.2 89.9 N.A. N.A. 69.3 51.6 60.7 48.6 43.1 N.A. N.A. 57.3
P-Site Identity: 100 0 13.3 60 N.A. 73.3 73.3 N.A. N.A. 0 6.6 6.6 13.3 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 13.3 46.6 86.6 N.A. 80 80 N.A. N.A. 0 20 33.3 40 6.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 9 0 25 0 0 9 0 0 9 9 0 17 9 % A
% Cys: 9 9 0 0 0 9 9 0 9 0 0 0 0 0 9 % C
% Asp: 0 0 9 0 0 0 0 0 0 9 0 0 9 9 9 % D
% Glu: 9 0 0 0 17 0 9 0 0 0 0 0 0 17 0 % E
% Phe: 9 0 9 9 0 9 0 0 0 0 9 0 0 9 0 % F
% Gly: 0 9 0 0 0 0 9 0 9 17 9 9 0 0 9 % G
% His: 0 0 25 0 0 25 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 9 9 17 0 17 0 0 0 0 0 % I
% Lys: 0 0 9 9 9 0 25 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 9 9 34 0 17 9 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 42 0 0 9 9 0 0 0 0 50 17 9 % N
% Pro: 9 0 0 9 9 9 0 0 9 0 0 9 9 9 0 % P
% Gln: 0 0 0 0 0 9 9 0 9 0 9 9 0 0 0 % Q
% Arg: 9 17 17 17 9 0 0 9 9 9 42 0 9 9 9 % R
% Ser: 17 42 9 9 25 17 17 0 34 0 25 34 0 17 34 % S
% Thr: 9 0 0 9 0 9 9 42 0 0 0 9 9 0 0 % T
% Val: 0 0 0 0 0 9 0 0 9 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 9 0 9 0 0 9 9 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _