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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH2
All Species:
13.03
Human Site:
T315
Identified Species:
26.06
UniProt:
P25021
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25021
NP_071640.1
359
40098
T315
A
N
R
N
S
H
K
T
S
L
R
S
N
A
S
Chimpanzee
Pan troglodytes
XP_001162258
428
48268
I339
E
R
Y
R
R
P
S
I
L
G
Q
T
V
P
C
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
N352
S
S
L
K
A
C
G
N
G
Y
S
S
N
S
N
Dog
Lupus familis
XP_546225
359
40183
T315
A
S
H
N
A
Q
E
T
S
L
R
S
N
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P97292
358
40361
T314
A
S
H
N
S
H
K
T
S
L
R
L
N
N
S
Rat
Rattus norvegicus
P25102
358
40235
T314
A
S
H
N
S
H
K
T
S
L
R
L
N
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425208
351
39363
L310
T
G
D
P
K
S
S
L
Q
K
G
Q
P
R
G
Frog
Xenopus laevis
O42574
385
43291
Y325
S
A
F
N
P
I
I
Y
C
R
S
P
D
F
R
Zebra Danio
Brachydanio rerio
NP_001038803
410
45665
I352
R
C
K
T
E
T
T
I
P
I
A
A
T
A
A
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
A361
C
S
S
S
A
V
Q
A
V
D
F
S
N
E
L
Fruit Fly
Dros. melanogaster
Q9VCZ3
508
56837
R431
P
Y
A
F
Y
F
C
R
R
G
R
G
R
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792332
363
40947
T306
F
R
R
R
E
S
N
T
Y
I
S
H
L
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
31
86.9
N.A.
84.9
86
N.A.
N.A.
57
33.7
45.1
29.5
28.9
N.A.
N.A.
40.2
Protein Similarity:
100
50
50.3
92.7
N.A.
90.2
89.9
N.A.
N.A.
69.3
51.6
60.7
48.6
43.1
N.A.
N.A.
57.3
P-Site Identity:
100
0
13.3
60
N.A.
73.3
73.3
N.A.
N.A.
0
6.6
6.6
13.3
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
46.6
86.6
N.A.
80
80
N.A.
N.A.
0
20
33.3
40
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
9
0
25
0
0
9
0
0
9
9
0
17
9
% A
% Cys:
9
9
0
0
0
9
9
0
9
0
0
0
0
0
9
% C
% Asp:
0
0
9
0
0
0
0
0
0
9
0
0
9
9
9
% D
% Glu:
9
0
0
0
17
0
9
0
0
0
0
0
0
17
0
% E
% Phe:
9
0
9
9
0
9
0
0
0
0
9
0
0
9
0
% F
% Gly:
0
9
0
0
0
0
9
0
9
17
9
9
0
0
9
% G
% His:
0
0
25
0
0
25
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
17
0
17
0
0
0
0
0
% I
% Lys:
0
0
9
9
9
0
25
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
9
9
34
0
17
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
42
0
0
9
9
0
0
0
0
50
17
9
% N
% Pro:
9
0
0
9
9
9
0
0
9
0
0
9
9
9
0
% P
% Gln:
0
0
0
0
0
9
9
0
9
0
9
9
0
0
0
% Q
% Arg:
9
17
17
17
9
0
0
9
9
9
42
0
9
9
9
% R
% Ser:
17
42
9
9
25
17
17
0
34
0
25
34
0
17
34
% S
% Thr:
9
0
0
9
0
9
9
42
0
0
0
9
9
0
0
% T
% Val:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
9
0
0
9
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _