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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH2
All Species:
31.21
Human Site:
T53
Identified Species:
62.42
UniProt:
P25021
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25021
NP_071640.1
359
40098
T53
N
R
R
L
R
N
L
T
N
C
F
I
V
S
L
Chimpanzee
Pan troglodytes
XP_001162258
428
48268
T55
R
Q
L
R
K
I
K
T
N
Y
F
I
V
S
L
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
T68
F
E
R
L
Q
T
V
T
N
Y
F
I
T
S
L
Dog
Lupus familis
XP_546225
359
40183
T53
N
R
R
L
R
S
L
T
N
C
F
I
V
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P97292
358
40361
T53
N
R
R
L
R
S
L
T
N
C
F
I
V
S
L
Rat
Rattus norvegicus
P25102
358
40235
T53
N
R
R
L
R
S
L
T
N
C
F
I
V
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425208
351
39363
A49
N
C
I
I
V
S
L
A
I
T
D
L
L
L
A
Frog
Xenopus laevis
O42574
385
43291
T70
N
Q
R
L
Q
T
L
T
N
V
F
I
T
S
L
Zebra Danio
Brachydanio rerio
NP_001038803
410
45665
T80
T
R
R
L
R
N
V
T
N
C
F
I
V
S
L
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
V74
F
R
H
L
R
S
K
V
T
N
A
F
V
V
S
Fruit Fly
Dros. melanogaster
Q9VCZ3
508
56837
T142
H
R
K
L
R
I
I
T
N
Y
F
V
V
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792332
363
40947
I47
V
V
L
V
I
I
I
I
A
T
I
F
G
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
31
86.9
N.A.
84.9
86
N.A.
N.A.
57
33.7
45.1
29.5
28.9
N.A.
N.A.
40.2
Protein Similarity:
100
50
50.3
92.7
N.A.
90.2
89.9
N.A.
N.A.
69.3
51.6
60.7
48.6
43.1
N.A.
N.A.
57.3
P-Site Identity:
100
46.6
53.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
66.6
86.6
26.6
60
N.A.
N.A.
0
P-Site Similarity:
100
60
66.6
100
N.A.
100
100
N.A.
N.A.
40
80
93.3
33.3
86.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
9
0
9
0
0
0
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
42
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
17
0
0
0
0
0
0
0
0
0
75
17
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
9
25
17
9
9
0
9
67
0
0
9
% I
% Lys:
0
0
9
0
9
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
17
75
0
0
50
0
0
0
0
9
9
9
75
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
17
0
0
75
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
59
59
9
59
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
42
0
0
0
0
0
0
0
75
9
% S
% Thr:
9
0
0
0
0
17
0
75
9
17
0
0
17
0
0
% T
% Val:
9
9
0
9
9
0
17
9
0
9
0
9
67
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _