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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH2
All Species:
18.48
Human Site:
Y299
Identified Species:
36.97
UniProt:
P25021
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25021
NP_071640.1
359
40098
Y299
N
R
D
F
R
T
G
Y
Q
Q
L
F
C
C
R
Chimpanzee
Pan troglodytes
XP_001162258
428
48268
F323
N
K
S
F
R
R
A
F
L
I
I
L
C
C
D
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
F336
S
P
D
F
R
I
A
F
Q
E
L
L
C
L
R
Dog
Lupus familis
XP_546225
359
40183
Y299
N
R
D
F
R
T
A
Y
Q
Q
L
F
R
C
R
Cat
Felis silvestris
Mouse
Mus musculus
P97292
358
40361
Y298
N
R
D
F
R
M
A
Y
Q
Q
L
F
H
C
K
Rat
Rattus norvegicus
P25102
358
40235
Y298
N
R
D
F
R
T
A
Y
Q
Q
L
F
H
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425208
351
39363
Y294
N
R
D
F
R
V
A
Y
Q
H
L
L
Q
C
W
Frog
Xenopus laevis
O42574
385
43291
F309
I
P
D
K
L
F
L
F
L
N
W
L
G
Y
A
Zebra Danio
Brachydanio rerio
NP_001038803
410
45665
Y336
N
R
D
F
R
S
A
Y
A
K
L
L
C
G
G
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
T345
A
D
F
R
K
A
F
T
T
I
L
G
C
S
K
Fruit Fly
Dros. melanogaster
Q9VCZ3
508
56837
F415
N
R
D
F
R
A
A
F
K
K
T
L
K
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792332
363
40947
F290
N
R
E
F
R
K
S
F
R
K
L
L
R
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
31
86.9
N.A.
84.9
86
N.A.
N.A.
57
33.7
45.1
29.5
28.9
N.A.
N.A.
40.2
Protein Similarity:
100
50
50.3
92.7
N.A.
90.2
89.9
N.A.
N.A.
69.3
51.6
60.7
48.6
43.1
N.A.
N.A.
57.3
P-Site Identity:
100
33.3
46.6
86.6
N.A.
73.3
80
N.A.
N.A.
60
6.6
53.3
13.3
33.3
N.A.
N.A.
40
P-Site Similarity:
100
53.3
66.6
86.6
N.A.
80
86.6
N.A.
N.A.
60
13.3
66.6
26.6
53.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
17
67
0
9
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
42
50
0
% C
% Asp:
0
9
75
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
9
84
0
9
9
42
0
0
0
34
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
9
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% H
% Ile:
9
0
0
0
0
9
0
0
0
17
9
0
0
0
0
% I
% Lys:
0
9
0
9
9
9
0
0
9
25
0
0
9
0
25
% K
% Leu:
0
0
0
0
9
0
9
0
17
0
75
59
0
17
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
34
0
0
9
0
0
% Q
% Arg:
0
67
0
9
84
9
0
0
9
0
0
0
17
0
34
% R
% Ser:
9
0
9
0
0
9
9
0
0
0
0
0
0
17
0
% S
% Thr:
0
0
0
0
0
25
0
9
9
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _