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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
15.45
Human Site:
S1214
Identified Species:
28.33
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1214
K
T
E
H
M
S
S
S
S
E
N
T
S
T
P
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1214
K
T
E
H
M
S
S
S
S
E
N
T
S
T
P
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
L720
P
G
S
C
V
P
S
L
Y
V
R
K
Q
R
A
Dog
Lupus familis
XP_536285
2273
247246
T690
I
N
Q
E
T
I
Q
T
Y
C
V
E
D
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
S1213
K
P
E
H
L
S
P
S
S
E
N
T
A
V
P
Rat
Rattus norvegicus
P70478
2842
310514
P1211
T
K
T
E
H
N
S
P
S
S
E
A
A
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1219
K
A
E
H
I
S
T
S
N
G
N
V
S
T
S
Chicken
Gallus gallus
XP_001233411
2232
244958
N649
V
S
S
L
I
A
T
N
E
D
H
R
Q
I
L
Frog
Xenopus laevis
P70039
2829
310863
S1220
K
E
Q
V
S
S
N
S
N
T
P
T
P
S
P
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
E1158
D
Y
S
L
K
Y
S
E
A
P
S
K
K
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
I834
E
G
Q
E
I
L
L
I
L
D
D
S
V
K
C
Honey Bee
Apis mellifera
XP_624558
2760
306907
N1175
E
L
K
G
D
T
R
N
M
P
Y
I
L
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
N1343
D
V
S
S
I
Y
T
N
S
R
A
A
S
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
6.6
13.3
N.A.
66.6
13.3
N.A.
53.3
0
33.3
6.6
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
13.3
26.6
N.A.
80
33.3
N.A.
73.3
46.6
60
20
N.A.
40
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
8
0
8
16
16
0
16
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% C
% Asp:
16
0
0
0
8
0
0
0
0
16
8
0
8
0
0
% D
% Glu:
16
8
31
24
0
0
0
8
8
24
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
16
0
8
0
0
0
0
0
8
0
0
0
16
0
% G
% His:
0
0
0
31
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
31
8
0
8
0
0
0
8
0
8
8
% I
% Lys:
39
8
8
0
8
0
0
0
0
0
0
16
8
8
0
% K
% Leu:
0
8
0
16
8
8
8
8
8
0
0
0
8
0
8
% L
% Met:
0
0
0
0
16
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
8
8
24
16
0
31
0
0
8
0
% N
% Pro:
8
8
0
0
0
8
8
8
0
16
8
0
8
0
39
% P
% Gln:
0
0
24
0
0
0
8
0
0
0
0
0
16
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
8
8
0
8
0
% R
% Ser:
0
8
31
8
8
39
39
39
39
8
8
8
31
16
8
% S
% Thr:
8
16
8
0
8
8
24
8
0
8
0
31
0
31
0
% T
% Val:
8
8
0
8
8
0
0
0
0
8
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
16
0
0
16
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _