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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
10
Human Site:
S1896
Identified Species:
18.33
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1896
E
S
E
A
K
V
T
S
H
T
E
L
T
S
N
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1896
E
S
E
A
K
V
T
S
H
T
E
L
T
S
N
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
L1371
L
V
P
G
R
R
A
L
P
V
P
V
Y
M
L
Dog
Lupus familis
XP_536285
2273
247246
A1341
Q
S
A
N
K
T
Q
A
V
T
K
H
P
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
C1894
D
S
E
A
K
V
T
C
R
P
E
P
N
S
S
Rat
Rattus norvegicus
P70478
2842
310514
C1894
D
S
E
A
K
V
T
C
H
T
E
P
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1901
E
A
D
A
N
A
S
S
H
P
E
P
S
T
N
Chicken
Gallus gallus
XP_001233411
2232
244958
N1300
A
K
K
Q
N
L
K
N
N
S
R
D
F
N
D
Frog
Xenopus laevis
P70039
2829
310863
Y1893
D
T
D
Q
K
V
K
Y
K
H
E
N
R
A
I
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
H1810
F
A
F
D
S
P
H
H
Y
T
P
I
E
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
K1485
E
R
E
R
K
D
E
K
L
L
Q
E
C
I
N
Honey Bee
Apis mellifera
XP_624558
2760
306907
N1828
S
E
C
L
E
N
I
N
P
P
S
L
F
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
D2265
V
D
S
Q
K
D
G
D
A
K
S
E
T
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
0
26.6
N.A.
53.3
66.6
N.A.
40
0
20
6.6
N.A.
26.6
6.6
N.A.
20
P-Site Similarity:
100
100
13.3
46.6
N.A.
66.6
86.6
N.A.
73.3
46.6
46.6
26.6
N.A.
33.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
39
0
8
8
8
8
0
0
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
16
0
0
0
0
8
0
0
% C
% Asp:
24
8
16
8
0
16
0
8
0
0
0
8
0
0
8
% D
% Glu:
31
8
39
0
8
0
8
0
0
0
47
16
8
0
8
% E
% Phe:
8
0
8
0
0
0
0
0
0
0
0
0
16
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
8
8
31
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
8
% I
% Lys:
0
8
8
0
62
0
16
8
8
8
8
0
0
0
0
% K
% Leu:
8
0
0
8
0
8
0
8
8
8
0
24
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
16
8
0
16
8
0
0
8
8
16
39
% N
% Pro:
0
0
8
0
0
8
0
0
16
24
16
24
8
0
0
% P
% Gln:
8
0
0
24
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
8
8
8
0
0
8
0
8
0
8
0
0
% R
% Ser:
8
39
8
0
8
0
8
24
0
8
16
0
16
39
24
% S
% Thr:
0
8
0
0
0
8
31
0
0
39
0
0
24
8
8
% T
% Val:
8
8
0
0
0
39
0
0
8
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _