KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
7.88
Human Site:
S1995
Identified Species:
14.44
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1995
K
E
T
E
P
P
D
S
Q
G
E
P
S
K
P
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1996
K
E
T
E
P
P
D
S
Q
G
E
P
S
K
P
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
K1462
E
Q
A
R
G
T
G
K
N
R
A
G
L
E
L
Dog
Lupus familis
XP_536285
2273
247246
P1432
S
Q
G
E
P
S
K
P
Q
A
S
G
Y
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
Q1995
E
A
E
P
A
N
S
Q
G
E
P
S
K
P
Q
Rat
Rattus norvegicus
P70478
2842
310514
Q1995
D
A
E
P
A
N
A
Q
G
Q
P
G
K
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
T1996
K
P
P
E
P
P
E
T
Q
I
E
S
S
R
P
Chicken
Gallus gallus
XP_001233411
2232
244958
R1391
S
G
Q
Q
P
S
N
R
T
Q
V
C
Q
K
H
Frog
Xenopus laevis
P70039
2829
310863
L1984
N
N
K
E
T
E
P
L
K
Q
T
G
T
S
E
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
F1905
V
C
D
E
K
Q
K
F
S
I
E
D
T
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
P1576
V
T
D
T
V
R
S
P
A
A
P
N
Q
G
N
Honey Bee
Apis mellifera
XP_624558
2760
306907
L1919
T
P
K
Q
K
R
T
L
A
K
E
R
Y
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
K2365
N
K
S
P
S
S
T
K
A
R
D
E
S
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
0
26.6
N.A.
0
0
N.A.
53.3
13.3
6.6
13.3
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
20
33.3
N.A.
6.6
0
N.A.
73.3
26.6
20
20
N.A.
0
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
16
0
8
0
24
16
8
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
16
0
0
0
16
0
0
0
8
8
0
0
0
% D
% Glu:
16
16
16
47
0
8
8
0
0
8
39
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
8
0
8
0
16
16
0
31
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% I
% Lys:
24
8
16
0
16
0
16
16
8
8
0
0
16
31
0
% K
% Leu:
0
0
0
0
0
0
0
16
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
0
0
0
16
8
0
8
0
0
8
0
0
8
% N
% Pro:
0
16
8
24
39
24
8
16
0
0
24
16
0
31
31
% P
% Gln:
0
16
8
16
0
8
0
16
31
24
0
0
16
0
16
% Q
% Arg:
0
0
0
8
0
16
0
8
0
16
0
8
0
8
0
% R
% Ser:
16
0
8
0
8
24
16
16
8
0
8
16
31
8
0
% S
% Thr:
8
8
16
8
8
8
16
8
8
0
8
0
16
0
16
% T
% Val:
16
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _