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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
13.64
Human Site:
S925
Identified Species:
25
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S925
E
R
N
A
L
R
R
S
S
A
A
H
T
H
S
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S925
E
R
N
A
L
R
R
S
S
A
A
H
T
H
S
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
G438
R
A
M
N
E
L
G
G
L
Q
A
V
A
E
L
Dog
Lupus familis
XP_536285
2273
247246
M408
G
Y
G
K
R
G
Q
M
K
P
S
I
E
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
S923
D
R
S
A
A
R
R
S
S
A
S
H
T
H
S
Rat
Rattus norvegicus
P70478
2842
310514
S923
E
R
T
A
A
R
R
S
S
A
S
H
T
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
A929
E
R
T
A
L
R
R
A
S
T
A
H
P
H
S
Chicken
Gallus gallus
XP_001233411
2232
244958
S367
L
H
G
N
D
K
D
S
V
L
L
G
N
S
R
Frog
Xenopus laevis
P70039
2829
310863
P925
E
R
N
S
Q
R
K
P
S
S
N
H
P
Q
S
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
E875
Q
I
A
V
V
M
E
E
V
Q
N
M
H
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
L551
C
E
P
Y
R
Q
I
L
R
Q
H
N
C
L
A
Honey Bee
Apis mellifera
XP_624558
2760
306907
S893
P
D
Q
E
S
T
C
S
Q
N
L
L
H
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
F936
S
N
S
Y
C
F
G
F
D
G
G
H
G
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
6.6
0
N.A.
73.3
73.3
N.A.
73.3
6.6
46.6
0
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
6.6
13.3
N.A.
93.3
80
N.A.
80
13.3
66.6
13.3
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
39
16
0
0
8
0
31
31
0
8
0
8
% A
% Cys:
8
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
8
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% D
% Glu:
39
8
0
8
8
0
8
8
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
0
0
8
16
8
0
8
8
8
8
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
54
16
39
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
0
8
8
0
8
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
24
8
0
8
8
8
16
8
0
24
8
% L
% Met:
0
0
8
0
0
8
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
8
24
16
0
0
0
0
0
8
16
8
8
0
0
% N
% Pro:
8
0
8
0
0
0
0
8
0
8
0
0
16
0
8
% P
% Gln:
8
0
8
0
8
8
8
0
8
24
0
0
0
8
0
% Q
% Arg:
8
47
0
0
16
47
39
0
8
0
0
0
0
0
8
% R
% Ser:
8
0
16
8
8
0
0
47
47
8
24
0
0
24
47
% S
% Thr:
0
0
16
0
0
8
0
0
0
8
0
0
31
0
0
% T
% Val:
0
0
0
8
8
0
0
0
16
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _