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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APC All Species: 18.18
Human Site: S932 Identified Species: 33.33
UniProt: P25054 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25054 NP_000029.2 2843 311646 S932 S S A A H T H S N T Y N F T K
Chimpanzee Pan troglodytes XP_001143509 2844 311637 S932 S S A A H T H S N T Y N F T K
Rhesus Macaque Macaca mulatta XP_001095216 2303 243755 L445 G L Q A V A E L L Q V D Y E M
Dog Lupus familis XP_536285 2273 247246 Y415 M K P S I E S Y S E D D E S K
Cat Felis silvestris
Mouse Mus musculus Q61315 2845 311071 S930 S S A S H T H S N T Y N F T K
Rat Rattus norvegicus P70478 2842 310514 P930 S S A S H T H P N T H N F A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511806 2844 309621 S936 A S T A H P H S S T Y S F P K
Chicken Gallus gallus XP_001233411 2232 244958 R374 S V L L G N S R G S K E A R A
Frog Xenopus laevis P70039 2829 310863 S932 P S S N H P Q S N P F T F T K
Zebra Danio Brachydanio rerio NP_001137312 2754 301074 G882 E V Q N M H L G M D D R S A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477152 2417 261266 A558 L R Q H N C L A I L L Q Q L K
Honey Bee Apis mellifera XP_624558 2760 306907 S900 S Q N L L H S S V E D N L P Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783363 3212 346162 V943 F D G G H G L V A R R S S T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 35 74.2 N.A. 90.4 90.1 N.A. 86.7 67.1 75 68 N.A. 23.8 22.8 N.A. 29.1
Protein Similarity: 100 99.5 49.4 76.1 N.A. 94.2 94.3 N.A. 92.7 72.2 84 78.2 N.A. 41 42 N.A. 45.1
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 73.3 N.A. 60 6.6 46.6 0 N.A. 6.6 20 N.A. 13.3
P-Site Similarity: 100 100 20 33.3 N.A. 100 86.6 N.A. 80 13.3 60 0 N.A. 20 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 31 31 0 8 0 8 8 0 0 0 8 16 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 8 24 16 0 0 0 % D
% Glu: 8 0 0 0 0 8 8 0 0 16 0 8 8 8 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 8 0 47 0 0 % F
% Gly: 8 0 8 8 8 8 0 8 8 0 0 0 0 0 8 % G
% His: 0 0 0 8 54 16 39 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 62 % K
% Leu: 8 8 8 16 8 0 24 8 8 8 8 0 8 8 0 % L
% Met: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 8 % M
% Asn: 0 0 8 16 8 8 0 0 39 0 0 39 0 0 0 % N
% Pro: 8 0 8 0 0 16 0 8 0 8 0 0 0 16 0 % P
% Gln: 0 8 24 0 0 0 8 0 0 8 0 8 8 0 8 % Q
% Arg: 0 8 0 0 0 0 0 8 0 8 8 8 0 8 0 % R
% Ser: 47 47 8 24 0 0 24 47 16 8 0 16 16 8 0 % S
% Thr: 0 0 8 0 0 31 0 0 0 39 0 8 0 39 0 % T
% Val: 0 16 0 0 8 0 0 8 8 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 31 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _