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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1D
All Species:
10.3
Human Site:
S515
Identified Species:
22.67
UniProt:
P25100
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25100
NP_000669.1
572
60463
S515
T
Q
L
R
A
K
V
S
S
L
S
H
K
I
R
Chimpanzee
Pan troglodytes
Q9N298
422
46153
F370
I
V
A
L
V
L
P
F
C
E
S
S
C
H
M
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
G365
R
L
L
C
H
C
G
G
R
L
P
R
E
P
C
Dog
Lupus familis
XP_542909
372
38265
G320
S
A
A
D
G
A
H
G
P
R
S
A
K
G
H
Cat
Felis silvestris
Mouse
Mus musculus
P97714
562
59839
S505
T
Q
L
R
A
K
V
S
S
L
S
H
K
F
R
Rat
Rattus norvegicus
P23944
561
59336
S505
T
Q
L
R
A
K
V
S
S
L
S
H
K
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506393
511
56733
R456
H
H
E
P
G
R
P
R
D
P
G
H
F
F
T
Chicken
Gallus gallus
XP_420871
511
57302
N455
A
Q
L
K
E
K
M
N
S
L
S
N
K
I
R
Frog
Xenopus laevis
Q91559
425
47998
S373
L
W
L
G
Y
T
N
S
L
I
N
P
L
I
Y
Zebra Danio
Brachydanio rerio
XP_697043
491
55838
N439
E
K
M
N
N
L
S
N
K
I
K
N
G
T
G
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
F371
I
V
A
L
V
L
P
F
C
A
E
N
C
Y
M
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
31.8
61.5
N.A.
79.7
85.4
N.A.
45.9
58.3
25.8
53.3
24.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.6
42.6
62.2
N.A.
82.6
87.9
N.A.
58
70.2
43
66
39.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
13.3
N.A.
93.3
100
N.A.
6.6
60
20
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
20
20
N.A.
93.3
100
N.A.
13.3
86.6
33.3
33.3
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
28
0
28
10
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
10
0
10
0
0
19
0
0
0
19
0
10
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
10
0
10
0
0
0
0
10
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
10
19
0
% F
% Gly:
0
0
0
10
19
0
10
19
0
0
10
0
10
10
10
% G
% His:
10
10
0
0
10
0
10
0
0
0
0
37
0
10
10
% H
% Ile:
19
0
0
0
0
0
0
0
0
19
0
0
0
37
0
% I
% Lys:
0
10
0
10
0
37
0
0
10
0
10
0
46
0
0
% K
% Leu:
10
10
55
19
0
28
0
0
10
46
0
0
10
0
0
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
19
% M
% Asn:
0
0
0
10
10
0
10
19
0
0
10
28
0
0
0
% N
% Pro:
0
0
0
10
0
0
28
0
10
10
10
10
0
10
0
% P
% Gln:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
28
0
10
0
10
10
10
0
10
0
0
37
% R
% Ser:
10
0
0
0
0
0
10
37
37
0
55
10
0
0
0
% S
% Thr:
28
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% T
% Val:
0
19
0
0
19
0
28
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _