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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADRA1D All Species: 10.61
Human Site: T507 Identified Species: 23.33
UniProt: P25100 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25100 NP_000669.1 572 60463 T507 L G P F R R P T T Q L R A K V
Chimpanzee Pan troglodytes Q9N298 422 46153 F362 I L C W L P F F I V A L V L P
Rhesus Macaque Macaca mulatta Q28524 418 44639 R357 P D F R S A F R R L L C H C G
Dog Lupus familis XP_542909 372 38265 A312 L R I H C R G A S A A D G A H
Cat Felis silvestris
Mouse Mus musculus P97714 562 59839 T497 L G P L Q R P T T Q L R A K V
Rat Rattus norvegicus P23944 561 59336 T497 L G P L Q R P T T Q L R A K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506393 511 56733 P448 S S T Y L S P P H H E P G R P
Chicken Gallus gallus XP_420871 511 57302 S447 T P F Q K P A S A Q L K E K M
Frog Xenopus laevis Q91559 425 47998 L365 P L R L E R T L L W L G Y T N
Zebra Danio Brachydanio rerio XP_697043 491 55838 K431 Q K S S F Q L K E K M N N L S
Tiger Blowfish Takifugu rubipres O42385 423 46982 F363 I F C W L P F F I V A L V L P
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 31.8 61.5 N.A. 79.7 85.4 N.A. 45.9 58.3 25.8 53.3 24.1 N.A. N.A. N.A. N.A.
Protein Similarity: 100 39.6 42.6 62.2 N.A. 82.6 87.9 N.A. 58 70.2 43 66 39.1 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 13.3 N.A. 86.6 86.6 N.A. 6.6 20 13.3 0 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 6.6 20 N.A. 93.3 93.3 N.A. 20 46.6 13.3 20 13.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 10 10 10 28 0 28 10 0 % A
% Cys: 0 0 19 0 10 0 0 0 0 0 0 10 0 10 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 10 0 10 0 10 0 0 % E
% Phe: 0 10 19 10 10 0 28 19 0 0 0 0 0 0 0 % F
% Gly: 0 28 0 0 0 0 10 0 0 0 0 10 19 0 10 % G
% His: 0 0 0 10 0 0 0 0 10 10 0 0 10 0 10 % H
% Ile: 19 0 10 0 0 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 10 0 0 10 0 10 0 10 0 37 0 % K
% Leu: 37 19 0 28 28 0 10 10 10 10 55 19 0 28 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 10 % N
% Pro: 19 10 28 0 0 28 37 10 0 0 0 10 0 0 28 % P
% Gln: 10 0 0 10 19 10 0 0 0 37 0 0 0 0 0 % Q
% Arg: 0 10 10 10 10 46 0 10 10 0 0 28 0 10 0 % R
% Ser: 10 10 10 10 10 10 0 10 10 0 0 0 0 0 10 % S
% Thr: 10 0 10 0 0 0 10 28 28 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 19 0 0 19 0 28 % V
% Trp: 0 0 0 19 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _