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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDNRA
All Species:
19.7
Human Site:
S397
Identified Species:
54.17
UniProt:
P25101
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25101
NP_001948.1
427
48722
S397
Q
S
K
S
L
M
T
S
V
P
M
N
G
T
S
Chimpanzee
Pan troglodytes
XP_509693
532
59607
S503
Q
S
F
E
E
K
Q
S
L
E
E
K
Q
S
C
Rhesus Macaque
Macaca mulatta
Q6H2Y3
398
44247
R369
T
T
L
A
V
M
G
R
V
P
G
T
G
N
M
Dog
Lupus familis
XP_853465
426
48505
S396
Q
S
K
S
L
M
T
S
V
P
M
N
G
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61614
427
48560
S397
Q
S
K
S
L
M
T
S
V
P
M
N
G
T
S
Rat
Rattus norvegicus
P26684
426
48226
S397
Q
S
K
S
L
M
T
S
V
P
M
N
G
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513438
427
48596
S397
Q
S
K
S
L
M
T
S
V
P
M
N
G
T
S
Chicken
Gallus gallus
Frog
Xenopus laevis
P32940
444
50154
P411
R
P
T
L
T
I
T
P
M
D
E
K
G
S
G
Zebra Danio
Brachydanio rerio
Q7SZP9
362
40631
K333
L
C
L
L
N
L
K
K
A
M
H
G
H
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
27.3
94.8
N.A.
92.2
92.7
N.A.
89.4
N.A.
49.5
25.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62
49.4
97.6
N.A.
96.2
95.7
N.A.
94.3
N.A.
68.4
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
26.6
100
N.A.
100
100
N.A.
100
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
46.6
100
N.A.
100
100
N.A.
100
N.A.
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
12
12
0
0
0
0
12
23
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
12
12
78
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
56
0
0
12
12
12
0
0
0
23
0
0
0
% K
% Leu:
12
0
23
23
56
12
0
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
67
0
0
12
12
56
0
0
12
12
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
56
0
12
0
% N
% Pro:
0
12
0
0
0
0
0
12
0
67
0
0
0
0
0
% P
% Gln:
67
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% Q
% Arg:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
67
0
56
0
0
0
67
0
0
0
0
0
23
67
% S
% Thr:
12
12
12
0
12
0
67
0
0
0
0
12
0
56
0
% T
% Val:
0
0
0
0
12
0
0
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _