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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2R All Species: 8.48
Human Site: T34 Identified Species: 20.74
UniProt: P25116 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25116 NP_001983.2 425 47441 T34 R R P E S K A T N A T L D P R
Chimpanzee Pan troglodytes XP_526888 707 77053 T316 G I I E S K A T N A T L D P R
Rhesus Macaque Macaca mulatta XP_001106136 425 47355 T34 R R P A S K A T N A T L D P R
Dog Lupus familis XP_546059 464 51544 A73 C L S K A T N A T V D P R S F
Cat Felis silvestris
Mouse Mus musculus P30558 430 47772 N39 E R T D A T V N P R S F F L R
Rat Rattus norvegicus P26824 432 48262 T41 M Y A T P Y A T P N P R S F F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513801 393 43481 L18 L R G A T V F L A A A V A S A
Chicken Gallus gallus Q5ZI82 357 41225
Frog Xenopus laevis P47749 420 47417 G33 N S D T Q A K G A H S N N M T
Zebra Danio Brachydanio rerio NP_001108318 413 46032 F30 N E T F I R S F S G F F L T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.1 98.1 79.3 N.A. 78.3 77.7 N.A. 33.6 28.9 52.9 43 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 59.5 98.3 83.4 N.A. 87.9 85.8 N.A. 51 47.2 72.4 65.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 93.3 0 N.A. 13.3 13.3 N.A. 13.3 0 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 93.3 13.3 N.A. 33.3 13.3 N.A. 26.6 0 13.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 20 20 10 40 10 20 40 10 0 10 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 0 0 10 0 30 0 0 % D
% Glu: 10 10 0 20 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 10 10 0 0 10 20 10 10 20 % F
% Gly: 10 0 10 0 0 0 0 10 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 30 10 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 0 0 0 0 10 0 0 0 30 10 10 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 20 0 0 0 0 0 10 10 30 10 0 10 10 0 0 % N
% Pro: 0 0 20 0 10 0 0 0 20 0 10 10 0 30 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 20 40 0 0 0 10 0 0 0 10 0 10 10 0 40 % R
% Ser: 0 10 10 0 30 0 10 0 10 0 20 0 10 20 0 % S
% Thr: 0 0 20 20 10 20 0 40 10 0 30 0 0 10 10 % T
% Val: 0 0 0 0 0 10 10 0 0 10 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _