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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2R All Species: 29.7
Human Site: Y140 Identified Species: 72.59
UniProt: P25116 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25116 NP_001983.2 425 47441 Y140 V K K P A V V Y M L H L A T A
Chimpanzee Pan troglodytes XP_526888 707 77053 Y422 V K K P A V V Y M L H L A T A
Rhesus Macaque Macaca mulatta XP_001106136 425 47355 Y140 V K K P A V V Y M L H L A T A
Dog Lupus familis XP_546059 464 51544 Y179 I K K P A V V Y M L H L A V A
Cat Felis silvestris
Mouse Mus musculus P30558 430 47772 Y145 V K K P A V V Y M L H L A M A
Rat Rattus norvegicus P26824 432 48262 Y147 V K K P A V V Y M L H L A M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513801 393 43481 L115 N L A L A D L L S V I W F P L
Chicken Gallus gallus Q5ZI82 357 41225 I79 A C C F P F Q I F Y H I Q R N
Frog Xenopus laevis P47749 420 47417 Y139 V R K P A V V Y M L N L A I A
Zebra Danio Brachydanio rerio NP_001108318 413 46032 Y129 P K K P A A I Y M M N L A C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.1 98.1 79.3 N.A. 78.3 77.7 N.A. 33.6 28.9 52.9 43 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 59.5 98.3 83.4 N.A. 87.9 85.8 N.A. 51 47.2 72.4 65.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 6.6 6.6 80 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 20 13.3 93.3 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 90 10 0 0 0 0 0 0 80 0 80 % A
% Cys: 0 10 10 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 10 0 0 10 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 10 10 0 0 10 10 0 10 0 % I
% Lys: 0 70 80 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 0 0 10 10 0 70 0 80 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 80 10 0 0 0 20 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 20 0 0 0 10 % N
% Pro: 10 0 0 80 10 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % T
% Val: 60 0 0 0 0 70 70 0 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _