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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM3
All Species:
0
Human Site:
S105
Identified Species:
0
UniProt:
P25205
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25205
NP_002379.2
808
90981
S105
F
Y
V
G
L
E
G
S
F
G
S
K
H
V
S
Chimpanzee
Pan troglodytes
XP_001151750
808
90957
Rhesus Macaque
Macaca mulatta
XP_001106966
808
90990
Dog
Lupus familis
XP_538960
916
102667
Cat
Felis silvestris
Mouse
Mus musculus
P25206
812
91528
Rat
Rattus norvegicus
XP_001070728
813
91641
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
Frog
Xenopus laevis
Q7ZXZ0
806
90528
Zebra Danio
Brachydanio rerio
NP_997732
807
90502
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511048
819
90900
Honey Bee
Apis mellifera
XP_625020
811
91329
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
Baker's Yeast
Sacchar. cerevisiae
P24279
971
107499
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
86
N.A.
92.9
93.3
N.A.
N.A.
81.4
80.1
75.9
N.A.
62.5
62.7
30.8
N.A.
Protein Similarity:
100
99.8
100
87.2
N.A.
96.6
97
N.A.
N.A.
92
90.7
88.1
N.A.
80
78.6
49.5
N.A.
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
0
0
0
N.A.
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
0
0
0
N.A.
Percent
Protein Identity:
N.A.
47.6
N.A.
49.3
39.8
N.A.
Protein Similarity:
N.A.
66
N.A.
68.1
54.7
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
100
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
0
100
0
0
100
0
0
100
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
100
0
0
0
100
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
100
0
0
0
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _