Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM3 All Species: 31.82
Human Site: Y99 Identified Species: 50
UniProt: P25205 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25205 NP_002379.2 808 90981 Y99 A K Q Y E E F Y V G L E G S F
Chimpanzee Pan troglodytes XP_001151750 808 90957 Y99 A K Q Y E E F Y V G L E G S F
Rhesus Macaque Macaca mulatta XP_001106966 808 90990 Y99 A K Q Y E E F Y V G L E G S F
Dog Lupus familis XP_538960 916 102667 Y207 A K Q Y E E F Y I G L E G S F
Cat Felis silvestris
Mouse Mus musculus P25206 812 91528 Y99 A K Q Y E E F Y I G L E G S F
Rat Rattus norvegicus XP_001070728 813 91641 Y99 A K Q Y E E F Y I G L E G S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMN2 812 91233 Y100 A K Q Y E D F Y I G L E G S F
Frog Xenopus laevis Q7ZXZ0 806 90528 Y99 A K Q Y E D F Y I G L E G S F
Zebra Danio Brachydanio rerio NP_997732 807 90502 F98 A K Q C E E F F I G L E G S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511048 819 90900 F96 A K M H E D L F V G F E G C F
Honey Bee Apis mellifera XP_625020 811 91329 F95 N Y V K E D L F I A F E G S F
Nematode Worm Caenorhab. elegans Q21902 759 84917 I84 L K N F D E D I E M K L R K F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q43704 768 85163 M95 L K E G E R V M V G F S G P F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL33 776 86338 L90 L K E G E L V L V G F E G Y F
Baker's Yeast Sacchar. cerevisiae P24279 971 107499 K154 V S S R H P W K L S F K G S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.5 86 N.A. 92.9 93.3 N.A. N.A. 81.4 80.1 75.9 N.A. 62.5 62.7 30.8 N.A.
Protein Similarity: 100 99.8 100 87.2 N.A. 96.6 97 N.A. N.A. 92 90.7 88.1 N.A. 80 78.6 49.5 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 86.6 80 N.A. 53.3 33.3 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 73.3 53.3 33.3 N.A.
Percent
Protein Identity: N.A. 47.6 N.A. 49.3 39.8 N.A.
Protein Similarity: N.A. 66 N.A. 68.1 54.7 N.A.
P-Site Identity: N.A. 40 N.A. 46.6 20 N.A.
P-Site Similarity: N.A. 46.6 N.A. 53.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 7 27 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 14 0 87 54 0 0 7 0 0 80 0 0 0 % E
% Phe: 0 0 0 7 0 0 60 20 0 0 34 0 0 0 100 % F
% Gly: 0 0 0 14 0 0 0 0 0 80 0 0 94 0 0 % G
% His: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 47 0 0 0 0 0 0 % I
% Lys: 0 87 0 7 0 0 0 7 0 0 7 7 0 7 0 % K
% Leu: 20 0 0 0 0 7 14 7 7 0 60 7 0 0 0 % L
% Met: 0 0 7 0 0 0 0 7 0 7 0 0 0 0 0 % M
% Asn: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % P
% Gln: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 7 0 7 0 0 0 0 0 0 7 0 0 % R
% Ser: 0 7 7 0 0 0 0 0 0 7 0 7 0 74 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 0 7 0 0 0 14 0 40 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 54 0 0 0 54 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _