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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFYB All Species: 24.55
Human Site: S129 Identified Species: 38.57
UniProt: P25208 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25208 NP_006157.1 207 22831 S129 M S T L G F D S Y V E P L K L
Chimpanzee Pan troglodytes XP_509327 199 22301 L126 F D S Y V E P L K L Y L Q K F
Rhesus Macaque Macaca mulatta XP_001097708 205 22580 S127 M S T L G F D S Y V E P L K L
Dog Lupus familis XP_532675 207 22797 S129 M S T L G F D S Y V E P L K L
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P63140 207 22769 S129 M S T L G F D S Y V E P L K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508705 205 22607 S127 M S T L G F D S Y V E P L K L
Chicken Gallus gallus P25207 205 22566 S127 M S T L G F D S Y V E P L K L
Frog Xenopus laevis P25211 122 13480 L49 F D S Y V E P L K L Y L Q K F
Zebra Danio Brachydanio rerio XP_001923556 205 22559 M128 M S T L G F D M Y V E P L K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394667 219 23322 N144 M T T L G F D N Y V E P L K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999685 197 21806 S124 E D I L Y A M S N L G F D N Y
Poplar Tree Populus trichocarpa XP_002323121 194 20827 T121 R E M E G E K T A A M G I V R
Maize Zea mays P25209 179 18977 D106 M A T L G F E D Y I E P L K V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23310 161 17168 A88 N G D D L L W A M T T L G F E
Baker's Yeast Sacchar. cerevisiae P13434 144 16135 E71 D A K E C M Q E C V S E L I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.5 99 98.5 N.A. N.A. 99 N.A. 97.5 96.6 54.5 80.6 N.A. N.A. 50.2 N.A. 48.3
Protein Similarity: 100 88.8 99 99 N.A. N.A. 99.5 N.A. 97.5 97 56 89.3 N.A. N.A. 61.6 N.A. 62.3
P-Site Identity: 100 6.6 100 100 N.A. N.A. 100 N.A. 100 100 6.6 93.3 N.A. N.A. 80 N.A. 13.3
P-Site Similarity: 100 20 100 100 N.A. N.A. 100 N.A. 100 100 20 93.3 N.A. N.A. 100 N.A. 20
Percent
Protein Identity: 45.4 43 N.A. 44.4 34.7 N.A.
Protein Similarity: 57 56.5 N.A. 54.5 50.7 N.A.
P-Site Identity: 6.6 66.6 N.A. 0 13.3 N.A.
P-Site Similarity: 20 93.3 N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 7 0 7 7 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 7 20 7 7 0 0 54 7 0 0 0 0 7 0 0 % D
% Glu: 7 7 0 14 0 20 7 7 0 0 60 7 0 0 7 % E
% Phe: 14 0 0 0 0 60 0 0 0 0 0 7 0 7 14 % F
% Gly: 0 7 0 0 67 0 0 0 0 0 7 7 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 7 0 0 7 7 0 % I
% Lys: 0 0 7 0 0 0 7 0 14 0 0 0 0 74 0 % K
% Leu: 0 0 0 67 7 7 0 14 0 20 0 20 67 0 47 % L
% Met: 60 0 7 0 0 7 7 7 7 0 7 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 7 7 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 14 0 0 0 0 60 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 14 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % R
% Ser: 0 47 14 0 0 0 0 47 0 0 7 0 0 0 7 % S
% Thr: 0 7 60 0 0 0 0 7 0 7 7 0 0 0 0 % T
% Val: 0 0 0 0 14 0 0 0 0 60 0 0 0 7 14 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 7 0 0 0 60 0 14 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _