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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFYB All Species: 37.27
Human Site: S99 Identified Species: 58.57
UniProt: P25208 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25208 NP_006157.1 207 22831 S99 E F I S F I T S E A S E R C H
Chimpanzee Pan troglodytes XP_509327 199 22301 R96 I T S E A S E R C H Q E K R K
Rhesus Macaque Macaca mulatta XP_001097708 205 22580 S97 E F I S F I T S E A S E R C H
Dog Lupus familis XP_532675 207 22797 S99 E F I S F I T S E A S E R C H
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P63140 207 22769 S99 E F I S F I T S E A S E R C H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508705 205 22607 S97 E F I S F I T S E A S E R C H
Chicken Gallus gallus P25207 205 22566 S97 E F I S F I T S E A S E R C H
Frog Xenopus laevis P25211 122 13480 R19 I T S E A S E R C H Q E K R K
Zebra Danio Brachydanio rerio XP_001923556 205 22559 S98 E F I S F I T S E A S E R C H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394667 219 23322 S114 E F I S F I T S E A S D R C H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999685 197 21806 F94 V Q E C V S E F I S F I T S E
Poplar Tree Populus trichocarpa XP_002323121 194 20827 L91 T I N G D D L L W A M T T L G
Maize Zea mays P25209 179 18977 S76 E F I S F I T S E A S D K C Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23310 161 17168 S58 E T V Q E C V S E F I S F I T
Baker's Yeast Sacchar. cerevisiae P13434 144 16135 W41 T L R E Q D R W L P I N N V A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.5 99 98.5 N.A. N.A. 99 N.A. 97.5 96.6 54.5 80.6 N.A. N.A. 50.2 N.A. 48.3
Protein Similarity: 100 88.8 99 99 N.A. N.A. 99.5 N.A. 97.5 97 56 89.3 N.A. N.A. 61.6 N.A. 62.3
P-Site Identity: 100 6.6 100 100 N.A. N.A. 100 N.A. 100 100 6.6 100 N.A. N.A. 93.3 N.A. 0
P-Site Similarity: 100 13.3 100 100 N.A. N.A. 100 N.A. 100 100 13.3 100 N.A. N.A. 100 N.A. 6.6
Percent
Protein Identity: 45.4 43 N.A. 44.4 34.7 N.A.
Protein Similarity: 57 56.5 N.A. 54.5 50.7 N.A.
P-Site Identity: 6.6 80 N.A. 20 0 N.A.
P-Site Similarity: 6.6 93.3 N.A. 26.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 14 0 0 0 0 67 0 0 0 0 7 % A
% Cys: 0 0 0 7 0 7 0 0 14 0 0 0 0 60 0 % C
% Asp: 0 0 0 0 7 14 0 0 0 0 0 14 0 0 0 % D
% Glu: 67 0 7 20 7 0 20 0 67 0 0 60 0 0 7 % E
% Phe: 0 60 0 0 60 0 0 7 0 7 7 0 7 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 14 0 0 0 0 54 % H
% Ile: 14 7 60 0 0 60 0 0 7 0 14 7 0 7 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 14 % K
% Leu: 0 7 0 0 0 0 7 7 7 0 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 7 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 7 0 7 7 0 0 0 0 0 14 0 0 0 7 % Q
% Arg: 0 0 7 0 0 0 7 14 0 0 0 0 54 14 0 % R
% Ser: 0 0 14 60 0 20 0 67 0 7 60 7 0 7 0 % S
% Thr: 14 20 0 0 0 0 60 0 0 0 0 7 14 0 7 % T
% Val: 7 0 7 0 7 0 7 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _