Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPST All Species: 28.48
Human Site: S143 Identified Species: 52.22
UniProt: P25325 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25325 NP_001013454.1 297 33178 S143 L R Q N L P L S S G K S Q P A
Chimpanzee Pan troglodytes XP_001159671 317 35336 S163 L R Q N L P L S S G K S Q P A
Rhesus Macaque Macaca mulatta XP_001084731 297 33430 S143 L R Q N F P L S S G K S Y P A
Dog Lupus familis XP_531744 298 33112 S143 L R L G L P L S S G K S R P A
Cat Felis silvestris
Mouse Mus musculus Q99J99 297 33005 S143 L N Q N L P I S S G K S H S E
Rat Rattus norvegicus P97532 297 32922 S143 L S Q N L P I S S G K S P S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517033 297 32917 G143 Q R E G R P L G S G K G R P V
Chicken Gallus gallus P25324 289 32268 T141 V K E G H P V T A E P S Q P A
Frog Xenopus laevis NP_001090542 299 33515 N144 L R E G L A V N L G K E P Q P
Zebra Danio Brachydanio rerio NP_001082815 296 32900 S141 L K E G H P V S Q Q Y S K P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17730 328 36929 G170 E L V K L P A G N F K A E D N
Sea Urchin Strong. purpuratus XP_784555 302 33055 S141 A G H P L C S S T A P S E V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08686 304 34200 S137 E F K Y P L D S S K V A A F S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 93.5 91.2 N.A. 84.1 84.8 N.A. 80.4 58.5 67.2 57.9 N.A. N.A. N.A. 25.2 46
Protein Similarity: 100 93 96.3 95.3 N.A. 92.2 92.9 N.A. 91.2 76.4 79.2 76 N.A. N.A. N.A. 44.8 64.2
P-Site Identity: 100 100 86.6 80 N.A. 66.6 66.6 N.A. 46.6 33.3 33.3 40 N.A. N.A. N.A. 20 20
P-Site Similarity: 100 100 86.6 86.6 N.A. 73.3 73.3 N.A. 60 73.3 53.3 66.6 N.A. N.A. N.A. 40 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 8 0 8 8 0 16 8 0 47 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % D
% Glu: 16 0 31 0 0 0 0 0 0 8 0 8 16 0 24 % E
% Phe: 0 8 0 0 8 0 0 0 0 8 0 0 0 8 0 % F
% Gly: 0 8 0 39 0 0 0 16 0 62 0 8 0 0 0 % G
% His: 0 0 8 0 16 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % I
% Lys: 0 16 8 8 0 0 0 0 0 8 70 0 8 0 0 % K
% Leu: 62 8 8 0 62 8 39 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 39 0 0 0 8 8 0 0 0 0 0 8 % N
% Pro: 0 0 0 8 8 77 0 0 0 0 16 0 16 54 8 % P
% Gln: 8 0 39 0 0 0 0 0 8 8 0 0 24 8 0 % Q
% Arg: 0 47 0 0 8 0 0 0 0 0 0 0 16 0 0 % R
% Ser: 0 8 0 0 0 0 8 70 62 0 0 70 0 16 8 % S
% Thr: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % T
% Val: 8 0 8 0 0 0 24 0 0 0 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _