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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPST All Species: 26.97
Human Site: T192 Identified Species: 49.44
UniProt: P25325 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25325 NP_001013454.1 297 33178 T192 A T G R F R G T E P E P R D G
Chimpanzee Pan troglodytes XP_001159671 317 35336 T212 A T G R F R G T E P E P R D G
Rhesus Macaque Macaca mulatta XP_001084731 297 33430 K192 A A G R F R G K E P E P R D G
Dog Lupus familis XP_531744 298 33112 T193 A A G R F R G T E P E P R D G
Cat Felis silvestris
Mouse Mus musculus Q99J99 297 33005 T192 A A G R F Q G T Q P E P R D G
Rat Rattus norvegicus P97532 297 32922 T192 A A G R F Q G T Q P E P R D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517033 297 32917 T192 A S G R F R G T E A E P R E G
Chicken Gallus gallus P25324 289 32268 F187 D S R P A G R F Q G T E L D Q
Frog Xenopus laevis NP_001090542 299 33515 L194 V E G R F R G L E P E P R E G
Zebra Danio Brachydanio rerio NP_001082815 296 32900 V190 A N G R F R G V E P E P R A N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17730 328 36929 T220 I R G Q F D G T Q E T G L D P
Sea Urchin Strong. purpuratus XP_784555 302 33055 K190 S K A R F L G K V P E P R E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08686 304 34200 T195 S L G R F E G T E P E P R S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 93.5 91.2 N.A. 84.1 84.8 N.A. 80.4 58.5 67.2 57.9 N.A. N.A. N.A. 25.2 46
Protein Similarity: 100 93 96.3 95.3 N.A. 92.2 92.9 N.A. 91.2 76.4 79.2 76 N.A. N.A. N.A. 44.8 64.2
P-Site Identity: 100 100 86.6 93.3 N.A. 80 80 N.A. 80 6.6 73.3 73.3 N.A. N.A. N.A. 33.3 53.3
P-Site Similarity: 100 100 86.6 93.3 N.A. 93.3 93.3 N.A. 93.3 20 80 73.3 N.A. N.A. N.A. 46.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 62 31 8 0 8 0 0 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 0 0 0 0 0 0 0 62 8 % D
% Glu: 0 8 0 0 0 8 0 0 62 8 85 8 0 24 0 % E
% Phe: 0 0 0 0 93 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 85 0 0 8 93 0 0 8 0 8 0 0 70 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 16 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 0 8 0 8 0 0 0 0 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 8 0 0 0 0 0 77 0 85 0 0 8 % P
% Gln: 0 0 0 8 0 16 0 0 31 0 0 0 0 0 8 % Q
% Arg: 0 8 8 85 0 54 8 0 0 0 0 0 85 0 0 % R
% Ser: 16 16 0 0 0 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 16 0 0 0 0 0 62 0 0 16 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _