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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPST All Species: 37.58
Human Site: Y272 Identified Species: 68.89
UniProt: P25325 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25325 NP_001013454.1 297 33178 Y272 G K P D V P I Y D G S W V E W
Chimpanzee Pan troglodytes XP_001159671 317 35336 Y292 G K P D V P I Y D G S W V E W
Rhesus Macaque Macaca mulatta XP_001084731 297 33430 Y272 G K P D V P I Y D G S W V E W
Dog Lupus familis XP_531744 298 33112 Y273 G K P D V P I Y D G S W V E W
Cat Felis silvestris
Mouse Mus musculus Q99J99 297 33005 Y272 G K S D V P V Y D G S W V E W
Rat Rattus norvegicus P97532 297 32922 Y272 G K P D V P V Y D G S W V E W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517033 297 32917 Y272 G K P D V A I Y D G S W V E W
Chicken Gallus gallus P25324 289 32268 V265 Y L C G K P D V A V Y D G S W
Frog Xenopus laevis NP_001090542 299 33515 Y274 G K E D V S I Y D G S W V E W
Zebra Danio Brachydanio rerio NP_001082815 296 32900 Y271 G H P G V S L Y D G A W S E W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17730 328 36929 R302 K P S Q N P P R V Y N G S L K
Sea Urchin Strong. purpuratus XP_784555 302 33055 Y275 G K K D V G V Y D G S W E E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08686 304 34200 A275 I K T A L E L A G V P N V R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 93.5 91.2 N.A. 84.1 84.8 N.A. 80.4 58.5 67.2 57.9 N.A. N.A. N.A. 25.2 46
Protein Similarity: 100 93 96.3 95.3 N.A. 92.2 92.9 N.A. 91.2 76.4 79.2 76 N.A. N.A. N.A. 44.8 64.2
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 93.3 13.3 86.6 60 N.A. N.A. N.A. 6.6 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 93.3 13.3 86.6 73.3 N.A. N.A. N.A. 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 8 8 0 8 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 70 0 0 8 0 77 0 0 8 0 0 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 0 0 0 8 77 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 77 0 0 16 0 8 0 0 8 77 0 8 8 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 47 0 0 0 0 0 0 0 0 % I
% Lys: 8 77 8 0 8 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 0 8 0 0 8 0 16 0 0 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 8 8 0 0 0 % N
% Pro: 0 8 54 0 0 62 8 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % R
% Ser: 0 0 16 0 0 16 0 0 0 0 70 0 16 8 0 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 77 0 24 8 8 16 0 0 70 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 77 0 0 77 % W
% Tyr: 8 0 0 0 0 0 0 77 0 8 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _