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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPST
All Species:
28.18
Human Site:
Y280
Identified Species:
51.67
UniProt:
P25325
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25325
NP_001013454.1
297
33178
Y280
D
G
S
W
V
E
W
Y
M
R
A
R
P
E
D
Chimpanzee
Pan troglodytes
XP_001159671
317
35336
Y300
D
G
S
W
V
E
W
Y
M
R
A
R
P
E
D
Rhesus Macaque
Macaca mulatta
XP_001084731
297
33430
Y280
D
G
S
W
V
E
W
Y
M
R
A
R
P
E
D
Dog
Lupus familis
XP_531744
298
33112
Y281
D
G
S
W
V
E
W
Y
M
R
A
Q
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99J99
297
33005
Y280
D
G
S
W
V
E
W
Y
M
R
A
Q
P
E
H
Rat
Rattus norvegicus
P97532
297
32922
Y280
D
G
S
W
V
E
W
Y
M
R
A
Q
P
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517033
297
32917
F280
D
G
S
W
V
E
W
F
M
R
A
Q
P
E
D
Chicken
Gallus gallus
P25324
289
32268
S273
A
V
Y
D
G
S
W
S
E
W
F
H
R
A
P
Frog
Xenopus laevis
NP_001090542
299
33515
Y282
D
G
S
W
V
E
W
Y
M
R
A
K
P
E
D
Zebra Danio
Brachydanio rerio
NP_001082815
296
32900
F279
D
G
A
W
S
E
W
F
T
K
A
A
P
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17730
328
36929
E310
V
Y
N
G
S
L
K
E
M
E
L
R
A
P
K
Sea Urchin
Strong. purpuratus
XP_784555
302
33055
A283
D
G
S
W
E
E
Y
A
Q
K
A
T
E
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08686
304
34200
Y283
G
V
P
N
V
R
L
Y
D
G
S
W
T
E
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
93.5
91.2
N.A.
84.1
84.8
N.A.
80.4
58.5
67.2
57.9
N.A.
N.A.
N.A.
25.2
46
Protein Similarity:
100
93
96.3
95.3
N.A.
92.2
92.9
N.A.
91.2
76.4
79.2
76
N.A.
N.A.
N.A.
44.8
64.2
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
86.6
6.6
93.3
53.3
N.A.
N.A.
N.A.
13.3
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
6.6
100
73.3
N.A.
N.A.
N.A.
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
0
0
77
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
77
0
0
8
0
0
0
0
8
0
0
0
0
8
39
% D
% Glu:
0
0
0
0
8
77
0
8
8
8
0
0
8
77
8
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
8
0
0
0
0
% F
% Gly:
8
77
0
8
8
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
24
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
16
0
8
0
0
8
% K
% Leu:
0
0
0
0
0
8
8
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
70
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
31
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
62
0
31
8
0
0
% R
% Ser:
0
0
70
0
16
8
0
8
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% T
% Val:
8
16
0
0
70
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
77
0
0
77
0
0
8
0
8
0
0
8
% W
% Tyr:
0
8
8
0
0
0
8
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _