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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPST All Species: 37.88
Human Site: Y85 Identified Species: 69.44
UniProt: P25325 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25325 NP_001013454.1 297 33178 Y85 G A E H F A E Y A G R L G V G
Chimpanzee Pan troglodytes XP_001159671 317 35336 Y105 G A E H F A E Y A G R L G V G
Rhesus Macaque Macaca mulatta XP_001084731 297 33430 Y85 S A Q H F A D Y A G R L G V G
Dog Lupus familis XP_531744 298 33112 Y85 S A E H F A E Y A G R L G V G
Cat Felis silvestris
Mouse Mus musculus Q99J99 297 33005 Y85 N A T H F A D Y A G S L G V S
Rat Rattus norvegicus P97532 297 32922 Y85 S A T H F A D Y A G S L G V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517033 297 32917 Y85 T A E S F A E Y A G K L G V G
Chicken Gallus gallus P25324 289 32268 Y83 S E A H F A D Y V G R L G V S
Frog Xenopus laevis NP_001090542 299 33515 Y86 T A D Q F S E Y A G S L G I S
Zebra Danio Brachydanio rerio NP_001082815 296 32900 Y83 T K G E F A D Y V G N L G I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17730 328 36929 Y102 R A D L F E E Y A Q M V G L N
Sea Urchin Strong. purpuratus XP_784555 302 33055 Y80 T P E F F A E Y V G E R G I C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08686 304 34200 A81 T K K V F D D A M S N L G V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 93.5 91.2 N.A. 84.1 84.8 N.A. 80.4 58.5 67.2 57.9 N.A. N.A. N.A. 25.2 46
Protein Similarity: 100 93 96.3 95.3 N.A. 92.2 92.9 N.A. 91.2 76.4 79.2 76 N.A. N.A. N.A. 44.8 64.2
P-Site Identity: 100 100 80 93.3 N.A. 66.6 66.6 N.A. 80 60 53.3 46.6 N.A. N.A. N.A. 40 46.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 73.3 73.3 N.A. 86.6 66.6 73.3 60 N.A. N.A. N.A. 60 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 8 0 0 77 0 8 70 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 16 0 0 8 47 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 39 8 0 8 54 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 8 100 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 8 0 0 0 0 0 0 85 0 0 100 0 47 % G
% His: 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 % I
% Lys: 0 16 8 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 0 8 0 0 0 0 0 0 0 85 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 16 0 0 0 8 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 8 0 0 0 0 0 8 0 0 0 0 8 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 39 8 0 0 0 % R
% Ser: 31 0 0 8 0 8 0 0 0 8 24 0 0 0 31 % S
% Thr: 39 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 24 0 0 8 0 70 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _