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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRD2 All Species: 19.39
Human Site: S779 Identified Species: 60.95
UniProt: P25440 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25440 NP_001106653.1 801 88061 S779 S R L S A S S S S S D S S S S
Chimpanzee Pan troglodytes XP_001167892 785 86765 S763 S R L S A S S S S S D S S S S
Rhesus Macaque Macaca mulatta XP_001115820 787 86976 S765 S R L S A S S S S S D S S S S
Dog Lupus familis XP_858054 745 81482 S723 G G P S R L S S S S S S G S G
Cat Felis silvestris
Mouse Mus musculus Q7JJ13 798 88048 S777 R L S A S S S S S D S S S S S
Rat Rattus norvegicus Q6MGA9 798 88032 S777 R L S A S S S S S D S S S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505872 1284 139915 S1262 G G P T R L S S S S S S E S G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FT54 369 42374 E348 L S G A Q K K E V S K K R N A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 97.1 60.6 N.A. 96.3 96.5 N.A. 40.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 97.3 69.1 N.A. 97.3 97.2 N.A. 47.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 46.6 N.A. 53.3 53.3 N.A. 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 46.6 N.A. 66.6 66.6 N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 28.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 38 38 0 0 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 25 38 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 13 0 0 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 25 25 13 0 0 0 0 0 0 0 0 0 13 0 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 13 13 0 0 0 13 13 0 0 0 % K
% Leu: 13 25 38 0 0 25 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 25 38 0 0 25 0 0 0 0 0 0 0 13 0 0 % R
% Ser: 38 13 25 50 25 63 88 88 88 75 50 88 63 88 63 % S
% Thr: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _