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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP5A1 All Species: 13.64
Human Site: S513 Identified Species: 23.08
UniProt: P25705 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25705 NP_001001937.1 553 59751 S513 K F E N A F L S H V V S Q H Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089681 584 62883 S544 K F E N A F L S H V I S Q H Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q03265 553 59734 S513 K F E N A F L S H V I S Q H Q
Rat Rattus norvegicus P15999 553 59735 S513 K F E S A F L S H V V S Q H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506958 616 66662 A576 K F E S A F L A H V I S Q H Q
Chicken Gallus gallus NP_989617 553 60168 A513 K F E S A F L A H V L S Q H Q
Frog Xenopus laevis P08428 545 58964 A505 K F E S A F L A H V K S Q H Q
Zebra Danio Brachydanio rerio NP_001070823 551 59725 Q512 K F E K A F L Q H V I S Q H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35381 552 59403 Q512 K F E K E F L Q H I K T S E Q
Honey Bee Apis mellifera XP_392639 547 59493 A507 A F E K E F L A H I R T S Q R
Nematode Worm Caenorhab. elegans Q9XXK1 538 57769 A498 K F E K E F L A H L R S S Q Q
Sea Urchin Strong. purpuratus NP_999743 551 59589 A511 K F E E Q F L A H I R S S H Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P07251 545 58589 F505 I G E F E S S F L S Y L K S N
Red Bread Mold Neurospora crassa P37211 551 59504 A511 Q W E A D F L A H L K T N E P
Conservation
Percent
Protein Identity: 100 N.A. 93.6 N.A. N.A. 97.4 96.7 N.A. 86.8 91.8 90.4 91.1 N.A. 81.7 81.7 79.1 79.2
Protein Similarity: 100 N.A. 94 N.A. N.A. 98.9 98.5 N.A. 88.6 96 94.2 95.3 N.A. 90.4 89.6 88.7 90.4
P-Site Identity: 100 N.A. 93.3 N.A. N.A. 93.3 93.3 N.A. 80 80 80 80 N.A. 46.6 33.3 53.3 60
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 100 100 93.3 86.6 N.A. 60 60 66.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 69.6 67.6
Protein Similarity: N.A. N.A. N.A. N.A. 82.4 81.1
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 58 0 0 50 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 100 8 29 0 0 0 0 0 0 0 0 15 0 % E
% Phe: 0 86 0 8 0 93 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 93 0 0 0 0 65 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 22 29 0 0 0 0 % I
% Lys: 79 0 0 29 0 0 0 0 0 0 22 0 8 0 0 % K
% Leu: 0 0 0 0 0 0 93 0 8 15 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 22 0 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 8 0 0 0 8 0 0 15 0 0 0 0 58 15 79 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 22 0 0 0 8 % R
% Ser: 0 0 0 29 0 8 8 29 0 8 0 72 29 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 58 15 0 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _