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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSS
All Species:
4.55
Human Site:
S99
Identified Species:
10
UniProt:
P25774
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25774
NP_004070.3
331
37496
S99
M
S
S
L
R
V
P
S
Q
W
Q
R
N
I
T
Chimpanzee
Pan troglodytes
XP_001171268
331
37376
S99
M
S
S
L
R
V
P
S
Q
W
Q
R
N
I
T
Rhesus Macaque
Macaca mulatta
NP_001027984
329
36923
H99
G
L
K
V
P
A
S
H
S
R
S
N
D
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O70370
340
38420
R107
M
G
A
L
R
I
S
R
Q
S
P
K
T
V
T
Rat
Rattus norvegicus
Q02765
330
36815
R97
M
G
S
L
R
I
P
R
P
W
N
R
S
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518002
618
66856
P385
T
M
T
G
L
K
V
P
P
A
R
T
Q
S
N
Chicken
Gallus gallus
Q90686
334
37200
P101
T
M
T
G
L
R
V
P
R
S
R
P
R
P
N
Frog
Xenopus laevis
NP_001086670
320
35636
R89
I
L
P
P
H
S
E
R
K
A
T
F
S
S
Q
Zebra Danio
Brachydanio rerio
NP_001017661
330
36275
P98
L
A
V
T
R
V
P
P
G
F
K
R
P
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
D138
H
K
Q
L
R
A
A
D
E
S
F
K
G
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43297
462
50948
K119
Y
L
G
A
K
M
E
K
K
G
E
R
R
T
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
55.5
N.A.
N.A.
71.7
73.4
N.A.
30.4
48.2
61
58.3
N.A.
43.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
71
N.A.
N.A.
84.1
83.3
N.A.
39.3
62.2
77
73.4
N.A.
57.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
33.3
53.3
N.A.
0
0
0
26.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
N.A.
N.A.
60
66.6
N.A.
13.3
20
20
53.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
19
10
0
0
19
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
19
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% F
% Gly:
10
19
10
19
0
0
0
0
10
10
0
0
10
10
0
% G
% His:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
19
0
0
0
0
0
0
0
19
0
% I
% Lys:
0
10
10
0
10
10
0
10
19
0
10
19
0
0
0
% K
% Leu:
10
28
0
46
19
0
0
0
0
0
0
0
0
0
10
% L
% Met:
37
19
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
19
0
19
% N
% Pro:
0
0
10
10
10
0
37
28
19
0
10
10
10
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
28
0
19
0
10
0
10
% Q
% Arg:
0
0
0
0
55
10
0
28
10
10
19
46
19
0
0
% R
% Ser:
0
19
28
0
0
10
19
19
10
28
10
0
19
19
10
% S
% Thr:
19
0
19
10
0
0
0
0
0
0
10
10
10
28
46
% T
% Val:
0
0
10
10
0
28
19
0
0
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _