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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSS
All Species:
13.64
Human Site:
T106
Identified Species:
30
UniProt:
P25774
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25774
NP_004070.3
331
37496
T106
S
Q
W
Q
R
N
I
T
Y
K
S
N
P
N
R
Chimpanzee
Pan troglodytes
XP_001171268
331
37376
T106
S
Q
W
Q
R
N
I
T
Y
K
S
N
P
N
Q
Rhesus Macaque
Macaca mulatta
NP_001027984
329
36923
L106
H
S
R
S
N
D
T
L
Y
I
P
D
W
E
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O70370
340
38420
T114
R
Q
S
P
K
T
V
T
F
R
S
Y
S
N
R
Rat
Rattus norvegicus
Q02765
330
36815
T104
R
P
W
N
R
S
G
T
L
K
S
S
S
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518002
618
66856
N392
P
P
A
R
T
Q
S
N
D
T
L
Y
S
P
D
Chicken
Gallus gallus
Q90686
334
37200
N108
P
R
S
R
P
R
P
N
G
T
L
Y
V
P
D
Frog
Xenopus laevis
NP_001086670
320
35636
Q96
R
K
A
T
F
S
S
Q
K
N
S
T
L
G
G
Zebra Danio
Brachydanio rerio
NP_001017661
330
36275
A105
P
G
F
K
R
P
T
A
E
Y
V
S
S
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
T145
D
E
S
F
K
G
V
T
F
I
S
P
A
H
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43297
462
50948
S126
K
K
G
E
R
R
T
S
L
R
Y
E
A
R
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
55.5
N.A.
N.A.
71.7
73.4
N.A.
30.4
48.2
61
58.3
N.A.
43.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
71
N.A.
N.A.
84.1
83.3
N.A.
39.3
62.2
77
73.4
N.A.
57.4
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
N.A.
N.A.
33.3
40
N.A.
0
0
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
N.A.
N.A.
60
60
N.A.
6.6
13.3
20
33.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
10
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
0
0
10
0
0
10
0
0
19
% D
% Glu:
0
10
0
10
0
0
0
0
10
0
0
10
0
10
0
% E
% Phe:
0
0
10
10
10
0
0
0
19
0
0
0
0
0
10
% F
% Gly:
0
10
10
0
0
10
10
0
10
0
0
0
0
10
19
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
19
0
0
19
0
0
0
0
0
% I
% Lys:
10
19
0
10
19
0
0
0
10
28
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
19
0
19
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
19
0
19
0
10
0
19
0
37
0
% N
% Pro:
28
19
0
10
10
10
10
0
0
0
10
10
19
19
0
% P
% Gln:
0
28
0
19
0
10
0
10
0
0
0
0
0
0
19
% Q
% Arg:
28
10
10
19
46
19
0
0
0
19
0
0
0
10
19
% R
% Ser:
19
10
28
10
0
19
19
10
0
0
55
19
37
10
0
% S
% Thr:
0
0
0
10
10
10
28
46
0
19
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
19
0
0
0
10
0
10
0
19
% V
% Trp:
0
0
28
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
28
10
10
28
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _