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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSS
All Species:
4.55
Human Site:
Y219
Identified Species:
10
UniProt:
P25774
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25774
NP_004070.3
331
37496
Y219
K
C
Q
Y
D
S
K
Y
R
A
A
T
C
S
K
Chimpanzee
Pan troglodytes
XP_001171268
331
37376
Y219
K
C
Q
Y
D
S
K
Y
R
A
A
T
C
S
K
Rhesus Macaque
Macaca mulatta
NP_001027984
329
36923
A219
Y
N
P
T
G
K
A
A
K
C
R
G
Y
R
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O70370
340
38420
K227
E
K
C
H
Y
N
S
K
N
R
A
A
T
C
S
Rat
Rattus norvegicus
Q02765
330
36815
N217
K
C
L
Y
D
P
K
N
R
A
A
T
C
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518002
618
66856
G505
P
C
R
Y
S
P
T
G
K
A
A
K
C
R
G
Chicken
Gallus gallus
Q90686
334
37200
G221
S
C
M
Y
S
P
T
G
K
A
A
K
C
R
G
Frog
Xenopus laevis
NP_001086670
320
35636
K209
C
H
Y
E
L
A
G
K
A
S
S
C
V
K
Y
Zebra Danio
Brachydanio rerio
NP_001017661
330
36275
Q218
S
C
R
Y
D
P
S
Q
R
A
A
N
C
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
V258
C
H
F
N
K
G
T
V
G
A
T
D
R
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43297
462
50948
N239
T
C
D
Q
I
R
K
N
A
K
V
V
T
I
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
55.5
N.A.
N.A.
71.7
73.4
N.A.
30.4
48.2
61
58.3
N.A.
43.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
71
N.A.
N.A.
84.1
83.3
N.A.
39.3
62.2
77
73.4
N.A.
57.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
6.6
73.3
N.A.
33.3
33.3
0
46.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
N.A.
N.A.
26.6
80
N.A.
46.6
40
20
60
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
19
64
64
10
0
0
0
% A
% Cys:
19
64
10
0
0
0
0
0
0
10
0
10
55
10
0
% C
% Asp:
0
0
10
0
37
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
10
10
10
19
10
0
0
10
0
10
19
% G
% His:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
28
10
0
0
10
10
37
19
28
10
0
19
0
10
19
% K
% Leu:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
10
0
19
10
0
0
10
0
0
0
% N
% Pro:
10
0
10
0
0
37
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
19
10
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
0
10
0
0
37
10
10
0
10
28
10
% R
% Ser:
19
0
0
0
19
19
19
0
0
10
10
0
0
28
19
% S
% Thr:
10
0
0
10
0
0
28
0
0
0
10
28
19
10
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
55
10
0
0
19
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _